{"id":"W2757377382","doi":"10.2741/4592","title":"L-NAME improves doxycycline and ML-7 cardioprotection from oxidative stress","year":2017,"lang":"en","type":"article","venue":"Frontiers in bioscience","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Cardioprotection; Contractility; Myosin light-chain kinase; Oxidative stress; Troponin I; Pharmacology; Chemistry; Ischemia; Matrix metalloproteinase; Nitric oxide; Nitric oxide synthase; Myosin; Biochemistry; Medicine; Cardiology; Enzyme; Myocardial infarction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001599665,0.0003301628,0.0005779716,0.0002741573,0.0001439296,0.0002315683,0.0002846818,0.0003209659,0.0009681244],"category_scores_gemma":[0.0001657441,0.0000883559,0.0002270397,0.0001240624,0.0002375422,0.0003302141,0.0002240506,0.0009303808,0.0001624711],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001219226,"about_ca_system_score_gemma":0.0003500144,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002858802,"about_ca_topic_score_gemma":0.0007810396,"domain_scores_codex":[0.9998723,0.0000248828,0.00001674974,0.00002180852,0.00002791024,0.00003632237],"domain_scores_gemma":[0.9998745,0.00001288554,0.0000325317,0.00001012753,0.00001543813,0.00005449666],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001984745,0.0008339543,0.00024392,0.000178463,0.00002080974,0.00006249526,0.00002521552,0.000127037,0.9826881,0.0001179257,0.0001681061,0.01354917],"study_design_scores_gemma":[0.000383975,0.008913944,0.007156157,0.00003573384,0.00009333833,0.0002299191,0.00003808501,0.001040023,0.9771128,0.000105976,0.004877898,0.00001232128],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877005,0.008542024,0.001577449,0.0002557991,0.0001412298,0.00004943305,0.0001342183,0.0001426158,0.001456835],"genre_scores_gemma":[0.993519,0.002690197,0.001745943,0.00009454834,0.00005888021,0.00004544537,0.0002332914,0.00001593508,0.001596744],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009681244,"threshold_uncertainty_score":0.003238738,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01301479257930837,"score_gpt":0.265553533585897,"score_spread":0.2525387410065886,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}