{"id":"W2757476094","doi":"10.1182/blood.v128.22.sci-1.sci-1","title":"Molecular Events Defining Human Clonal Hematopoiesis at Single Cell Resolution","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"","keywords":"Progenitor cell; Biology; Haematopoiesis; Stem cell; Myeloid; Immunology; Cell biology; Megakaryocyte; Lymphopoiesis; Multipotent Stem Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004849253,0.0001789433,0.0003055219,0.0008476457,0.00023729,0.000920467,0.0002916894,0.0005481905,0.002560208],"category_scores_gemma":[0.000600266,0.0002708136,0.0001738731,0.0004263794,0.0004124331,0.0006776914,0.0005367699,0.0009375259,0.001462852],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002902668,"about_ca_system_score_gemma":0.0001952922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003376949,"about_ca_topic_score_gemma":0.0005013809,"domain_scores_codex":[0.9998246,0.00002504789,0.00001173044,0.00005353573,0.0000632852,0.00002185264],"domain_scores_gemma":[0.9997366,0.00009802015,0.00005083662,0.00003721565,0.0000443916,0.00003290235],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001222124,0.00002418564,0.001972546,0.0001906601,0.00001580095,0.0003838736,0.0002848184,0.0003063882,0.9503593,0.01208189,0.001723984,0.03253441],"study_design_scores_gemma":[0.00003346287,0.0002801243,0.03883479,0.0001515224,0.00008143589,0.005121485,0.0004516992,0.00536953,0.7715816,0.01800994,0.1600228,0.0000616528],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6026578,0.06124619,0.2505831,0.00219391,0.0006850173,0.0003384537,0.004778177,0.001806512,0.07571088],"genre_scores_gemma":[0.8607042,0.02103253,0.1039787,0.001047289,0.0003796224,0.0002228336,0.003109173,0.0002031382,0.009322521],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002560208,"threshold_uncertainty_score":0.008564711,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01137091082341908,"score_gpt":0.2119270015618569,"score_spread":0.2005560907384378,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}