{"id":"W2757485969","doi":"10.1016/j.cjca.2017.07.319","title":"MODELING THE DILATED CARDIOMYOPATHY WITH ATAXIA SYNDROME (DCMA), A PEDIATRIC MITOCHONDRIAL CARDIOMYOPATHY, USING CARDIOMYOCYTES DERIVED FROM INDUCED PLURIPOTENT STEM CELLS","year":2017,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Calgary Laboratory Services","funders":"","keywords":"Medicine; Induced pluripotent stem cell; Cardiomyopathy; Dilated cardiomyopathy; Heart failure; Internal medicine; Transplantation; Cardiology; Bioinformatics; Embryonic stem cell; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001123901,0.0002670244,0.0001345897,0.0001605804,0.0001315889,0.0002576893,0.000419136,0.0003832211,0.0006062245],"category_scores_gemma":[0.0001348393,0.0001204211,0.0002158607,0.00009453011,0.0001710962,0.0001717898,0.0002751981,0.0003407315,0.00009536561],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001953446,"about_ca_system_score_gemma":0.0003328206,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00177317,"about_ca_topic_score_gemma":0.002778362,"domain_scores_codex":[0.9999471,0.00001017727,0.000003045177,0.000009982865,0.00002067133,0.000009036382],"domain_scores_gemma":[0.9999493,0.00001466861,0.00001408954,0.000005341972,0.000005646009,0.00001095983],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.00009164184,0.0001372413,0.004106292,0.0001437412,0.0000481628,0.0006288857,0.00008881385,0.3249689,0.6427746,0.01533294,0.0006902546,0.01098852],"study_design_scores_gemma":[0.00005120806,0.0002849336,0.002203058,0.00001792213,0.00006095845,0.0003501643,0.00006717654,0.8873668,0.1005997,0.003972574,0.005005989,0.00001958857],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8400239,0.0004397856,0.1522911,0.0003833834,0.0001163664,0.00009343932,0.0006156518,0.0003234489,0.00571291],"genre_scores_gemma":[0.9599026,0.0003682232,0.03719957,0.00004478476,0.00001056649,0.00004873603,0.0002552495,0.00003196053,0.002138464],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00177317,"threshold_uncertainty_score":0.003525734,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01680679829154207,"score_gpt":0.2400275150085325,"score_spread":0.2232207167169904,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}