{"id":"W2757528943","doi":"10.3390/molecules22101632","title":"Investigation of the N-Terminus Amino Function of Arg10-Teixobactin","year":2017,"lang":"en","type":"article","venue":"Molecules","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Population and Public Health; Ministerio de Asuntos Económicos y Transformación Digital, Gobierno de España; Inyuvesi Yakwazulu-Natali; Generalitat de Catalunya; King Saud University; National Research Foundation","keywords":"Peptide; Residue (chemistry); N-terminus; Stereochemistry; Chemistry; C-terminus; Depsipeptide; Mycobacterium tuberculosis; Function (biology); Biochemistry; Amino acid; Peptide sequence; Biology; Cell biology; Tuberculosis; Gene; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001044421,0.0001824426,0.0001118347,0.00006044389,0.00006694557,0.0001361056,0.0001304234,0.0002101416,0.0004864969],"category_scores_gemma":[0.0001765381,0.00004222716,0.0001364863,0.00007123536,0.0001354056,0.0001810321,0.0000991462,0.0002654291,0.0001965901],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001210345,"about_ca_system_score_gemma":0.0001277617,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003571783,"about_ca_topic_score_gemma":0.0002255372,"domain_scores_codex":[0.9999477,0.00001365343,0.000004389551,0.000008322186,0.00001428233,0.00001166786],"domain_scores_gemma":[0.9998844,0.00003749995,0.00002917506,0.000009038763,0.00001855886,0.00002133982],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001963077,0.00001770763,0.0002912708,0.000024051,0.000002411785,0.0001264286,0.00001102304,0.00008424635,0.9984736,0.00005501167,0.000005601278,0.0007123484],"study_design_scores_gemma":[0.00001517494,0.0004097249,0.005057884,0.000008766247,0.00001623814,0.0005894552,0.00004498806,0.0009569592,0.9906088,0.00004644403,0.002240886,0.00000455144],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981084,0.000497842,0.0007211351,0.00002656341,0.000006663824,0.000006900844,0.00005832489,0.000002775239,0.0005714082],"genre_scores_gemma":[0.9976159,0.0004148285,0.001007551,0.0000291227,0.000006139381,0.000005171622,0.0001913035,0.000004537013,0.0007253661],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004864969,"threshold_uncertainty_score":0.001627505,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02324789976690982,"score_gpt":0.238043933536485,"score_spread":0.2147960337695752,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}