{"id":"W2757746583","doi":"10.1210/en.2017-00263","title":"Insulin-Deficient Mouse<i>β</i>-Cells Do Not Fully Mature but Can Be Remedied Through Insulin Replacement by Islet Transplantation","year":2017,"lang":"en","type":"article","venue":"Endocrinology","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Canadian Diabetes Association","keywords":"Insulin; Biology; Internal medicine; Endocrinology; Transplantation; Islet; Insulin oscillation; Insulin receptor; Insulin resistance; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004529173,0.001119706,0.0004995589,0.0007268816,0.0002615517,0.0008463604,0.0006870819,0.0007053541,0.003810199],"category_scores_gemma":[0.0002726028,0.0006030092,0.0006735152,0.0003183493,0.0005620541,0.0006381934,0.0004211096,0.002700448,0.002065606],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003050173,"about_ca_system_score_gemma":0.0002563098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003257431,"about_ca_topic_score_gemma":0.0004807101,"domain_scores_codex":[0.9995377,0.00003518619,0.00008566604,0.0001352619,0.0001201995,0.0000860028],"domain_scores_gemma":[0.9991077,0.0001017161,0.0002925984,0.0001448569,0.00006124639,0.0002918543],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009259411,0.0000379205,0.000197416,0.0000223772,0.000006711142,0.0000793594,0.00002102408,0.00002728919,0.998599,0.0002055035,0.0000639749,0.0006469294],"study_design_scores_gemma":[0.00005961727,0.0003492086,0.005331469,0.00002712646,0.00003402826,0.0009742561,0.00006474653,0.0005835917,0.9844031,0.0001567478,0.00800383,0.00001219749],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.971113,0.002005827,0.01261749,0.0005005536,0.000305196,0.0001981025,0.004728321,0.001209235,0.007322268],"genre_scores_gemma":[0.9466438,0.002388321,0.01302166,0.0005159125,0.00009092607,0.0004641234,0.007581871,0.001277637,0.02801588],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003810199,"threshold_uncertainty_score":0.01274639,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02281189337677033,"score_gpt":0.2736227328115995,"score_spread":0.2508108394348292,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}