{"id":"W2757849159","doi":"10.3389/fmicb.2017.01956","title":"pH-Dependant Antifungal Activity of Valproic Acid against the Human Fungal Pathogen Candida albicans","year":2017,"lang":"en","type":"article","venue":"Frontiers in Microbiology","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier universitaire de Québec; Université de Montréal; Hôpital Maisonneuve-Rosemont; Université Laval","funders":"Fonds de Recherche du Québec - Santé; Centre Hospitalier Universitaire de Québec; Concordia University; Canada Foundation for Innovation; University of Pittsburgh; Université de Montréal; Université Laval","keywords":"Candida albicans; Microbiology; Corpus albicans; Vacuole; Biology; Antifungal drug; Valproic Acid; Pharmacology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001065873,0.0001968765,0.0001791494,0.0001638053,0.0001022696,0.0002489286,0.0001078558,0.0001901035,0.0006499249],"category_scores_gemma":[0.0001657877,0.00006608063,0.0001803104,0.0001282514,0.0001331951,0.0001423884,0.0001518312,0.0002405929,0.0001240773],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009257055,"about_ca_system_score_gemma":0.000175818,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004785866,"about_ca_topic_score_gemma":0.0005203307,"domain_scores_codex":[0.99991,0.00002547282,0.00001167361,0.00001241862,0.00002282942,0.00001755916],"domain_scores_gemma":[0.9999434,0.00001702329,0.00001162686,0.00000643751,0.0000095173,0.00001191213],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001518104,0.00001462136,0.0001965504,0.00005652765,0.000004202315,0.00005933189,0.0000100374,0.00006072258,0.9964656,0.00003303511,0.00002327307,0.002924392],"study_design_scores_gemma":[0.00001750437,0.000383835,0.00641485,0.00001377967,0.00001648138,0.0004512238,0.00002725774,0.0002283451,0.9905161,0.00004768424,0.001878924,0.000003995306],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889353,0.008176755,0.0007785212,0.000111493,0.00002378706,0.00001781103,0.0003763399,0.0000240714,0.001555974],"genre_scores_gemma":[0.9959717,0.002129208,0.001096089,0.00004125391,0.00001090781,0.000007414272,0.000194445,0.000005566384,0.0005432764],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006499249,"threshold_uncertainty_score":0.002174258,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01184422589260787,"score_gpt":0.2358645704460622,"score_spread":0.2240203445534543,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}