{"id":"W2758397052","doi":"10.1093/ofid/ofx163.1400","title":"Microbiome Profile is Distinct in Patients with Successful Response to Microbiota-Based Drug RBX2660 Relative to Placebo Responders","year":2017,"lang":"en","type":"article","venue":"Open Forum Infectious Diseases","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Placebo; Microbiome; Medicine; Internal medicine; Gastroenterology; Biology; Pathology; Bioinformatics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002527177,0.0003541073,0.0003431634,0.0002160892,0.0007116591,0.0003936249,0.0008481396,0.0001304371,0.0001339319],"category_scores_gemma":[0.0003339234,0.0003193081,0.00009465111,0.0002087396,0.000140059,0.00004685849,0.0007136576,0.0001351129,0.0001597825],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001771008,"about_ca_system_score_gemma":0.0005362022,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007490723,"about_ca_topic_score_gemma":0.002646027,"domain_scores_codex":[0.9978417,0.0002300914,0.0003121896,0.0008443397,0.0001304244,0.0006413237],"domain_scores_gemma":[0.9980522,0.00004553717,0.0002280935,0.00109308,0.0001897791,0.0003912588],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02197897,0.0007022876,0.8588275,0.00004252894,0.00006791102,0.00001088889,0.000180439,0.00002952667,0.07066241,0.00001086001,0.04717088,0.0003158489],"study_design_scores_gemma":[0.006293488,0.001637456,0.9417642,0.0001766497,0.00003622375,0.000002419102,0.00007972812,0.000001914286,0.01858963,0.00001847502,0.03079547,0.0006042877],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917375,0.00002985863,0.00006981015,0.002915122,0.0001538795,0.00261376,0.00124349,0.00002231285,0.001214254],"genre_scores_gemma":[0.993373,0.000001557152,0.0002920199,0.003016068,0.00002712724,0.0002072457,0.0003973823,0.00006286107,0.002622748],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0829368,"threshold_uncertainty_score":0.9999259,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005524981033940137,"score_gpt":0.2713536403336236,"score_spread":0.2658286592996835,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}