{"id":"W2758439028","doi":"10.1016/j.cryobiol.2017.09.005","title":"A toxicity cost function approach to optimal CPA equilibration in tissues","year":2017,"lang":"en","type":"article","venue":"Cryobiology","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":47,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Biomedical Imaging and Bioengineering; National Institute of Child Health and Human Development; Natural Sciences and Engineering Research Council of Canada","keywords":"Cryopreservation; Toxicity; Function (biology); Thermal diffusivity; Biomedical engineering; Chemistry; Biological system; Computer science; Materials science; Biology; Physics; Cell biology; Thermodynamics; Embryo; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001725247,0.001381345,0.001211793,0.0009869984,0.0007325773,0.001660934,0.002080991,0.002446998,0.006044579],"category_scores_gemma":[0.004493556,0.0006876513,0.0008993364,0.0008267168,0.0009932914,0.002068211,0.001882124,0.001850879,0.0005826251],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001934987,"about_ca_system_score_gemma":0.001973306,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002947288,"about_ca_topic_score_gemma":0.002219411,"domain_scores_codex":[0.9995316,0.0001507202,0.00001740088,0.00008109921,0.0001408677,0.0000783413],"domain_scores_gemma":[0.9988151,0.0006315878,0.0001101836,0.00008505351,0.0002725442,0.00008560092],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.00008358469,0.00009747803,0.0002974604,0.0001167019,0.00003028903,0.00007617436,0.00003614321,0.9334638,0.005882149,0.03000969,0.002001246,0.02790526],"study_design_scores_gemma":[0.00001053059,0.00006285003,0.0001656192,0.0000161995,0.0000203838,0.00004251023,0.00001494989,0.9851443,0.001579748,0.01166071,0.001272343,0.00000986855],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.01533584,0.0004242201,0.9723873,0.001055634,0.00009502205,0.0001051636,0.0001046521,0.0002405208,0.01025156],"genre_scores_gemma":[0.6633976,0.0008890982,0.3018743,0.0007700163,0.0002227744,0.0006747509,0.000285925,0.0007502428,0.03113526],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.006044579,"threshold_uncertainty_score":0.02022111,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05665310186991196,"score_gpt":0.331074377806154,"score_spread":0.274421275936242,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}