{"id":"W2758738264","doi":"10.3389/fendo.2017.00249","title":"Innate Viral Receptor Signaling Determines Type 1 Diabetes Onset","year":2017,"lang":"en","type":"review","venue":"Frontiers in Endocrinology","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Juvenile Diabetes Research Foundation International","keywords":"Immunology; Innate immune system; Biology; Coxsackievirus; Antigen; Pattern recognition receptor; Immune system; Receptor; Disease; Enterovirus; Medicine; Virus; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002965729,0.0005093936,0.0007541767,0.0008826178,0.0001357034,0.0006342276,0.0004565115,0.0006892242,0.002587187],"category_scores_gemma":[0.000328315,0.0001645767,0.000240102,0.0007952024,0.0003808554,0.0006477158,0.0004923837,0.001193528,0.001869137],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004725086,"about_ca_system_score_gemma":0.0006249996,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005316401,"about_ca_topic_score_gemma":0.0007487786,"domain_scores_codex":[0.9999048,0.00001673522,0.00001255543,0.00002610019,0.00002547529,0.00001441205],"domain_scores_gemma":[0.9998767,0.00003942686,0.00002436921,0.00000461031,0.00003426841,0.00002062673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001755806,0.00003813535,0.0006530476,0.005947753,0.00005859457,0.0002241298,0.000039885,0.0001923202,0.003876875,0.003253819,0.0166847,0.9688552],"study_design_scores_gemma":[0.00002344223,0.0001095937,0.003329449,0.002244569,0.0001210853,0.00191892,0.00007878359,0.0001012855,0.00158293,0.00278711,0.9876798,0.00002295547],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002669859,0.9983197,0.0001027838,0.0002484323,0.0001755737,0.000002068143,0.00002105013,0.00000738431,0.0008560311],"genre_scores_gemma":[0.001870569,0.9970481,0.0001039894,0.0001476757,0.0001507499,0.000003429123,0.0000403877,0.000001605374,0.0006335643],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002587187,"threshold_uncertainty_score":0.008655071,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02506227337943625,"score_gpt":0.3018897793837401,"score_spread":0.2768275060043038,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}