{"id":"W2758738264","doi":"10.3389/fendo.2017.00249","title":"Innate Viral Receptor Signaling Determines Type 1 Diabetes Onset","year":2017,"lang":"en","type":"review","venue":"Frontiers in Endocrinology","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Juvenile Diabetes Research Foundation International","keywords":"Immunology; Innate immune system; Biology; Coxsackievirus; Antigen; Pattern recognition receptor; Immune system; Receptor; Disease; Enterovirus; Medicine; Virus; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001438364,0.0005072611,0.001452751,0.0002675815,0.0001166373,0.00005351926,0.0008155703,0.0006450812,0.00002659185],"category_scores_gemma":[0.0003540416,0.0004810473,0.0003816226,0.0001138223,0.0002294545,0.000006953847,0.0003124296,0.0004090486,0.00005010988],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005799016,"about_ca_system_score_gemma":0.000213598,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001004903,"about_ca_topic_score_gemma":0.00001150089,"domain_scores_codex":[0.9975227,0.0002454015,0.0005320159,0.0007046941,0.00009733421,0.0008978855],"domain_scores_gemma":[0.9987076,0.00002645177,0.0004648158,0.0006651063,0.00005748102,0.00007856204],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001432064,0.00005973882,0.004481662,0.0009710938,0.000430708,0.00001865657,0.000008549377,0.000002015259,0.00007025267,0.000006831754,0.03217692,0.9617593],"study_design_scores_gemma":[0.0003400758,0.0001785703,0.00001803699,0.0007859853,0.0001636599,0.000004294419,0.00001677324,0.00000354137,0.0001804381,0.00008466669,0.9977135,0.0005104339],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003714056,0.9919429,0.00001130694,0.00002721191,0.003208424,0.0003629031,0.0001071627,0.00002425519,0.0006018022],"genre_scores_gemma":[0.0005016596,0.995447,0.0007700093,0.00009267759,0.0003079567,0.0001098617,0.001121318,0.0000854208,0.001564094],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9655366,"threshold_uncertainty_score":0.9997641,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02506227337943625,"score_gpt":0.3018897793837401,"score_spread":0.2768275060043038,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}