{"id":"W2759131359","doi":"10.1016/j.ijrobp.2017.06.1994","title":"Targeting Lactate Transporters MCT-1 and MCT-4 to Inhibit the Growth of Hypoxic HNSCC Cells In Vitro","year":2017,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Medicine; In vitro; Transporter; Cancer research; Pharmacology; Cell biology; Biochemistry; Gene; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001207089,0.000206087,0.0002406555,0.0001600433,0.0001751572,0.0002082912,0.0002242557,0.0001955934,0.001260397],"category_scores_gemma":[0.00008402641,0.000117455,0.0002537956,0.0001638647,0.0001676213,0.000147656,0.0001381256,0.0004851144,0.0002369353],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004656945,"about_ca_system_score_gemma":0.0004884586,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004711844,"about_ca_topic_score_gemma":0.006293009,"domain_scores_codex":[0.9999037,0.00001109942,0.000005786349,0.00001215982,0.00002887835,0.00003833948],"domain_scores_gemma":[0.9999683,0.000006904855,0.000006107184,0.000004273251,0.000007165657,0.000007319869],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004013591,0.0001944651,0.0003173228,0.00008295137,0.00001812537,0.00004338069,0.00003991225,0.0006097537,0.9937671,0.0003109693,0.0003852279,0.003829393],"study_design_scores_gemma":[0.00006886242,0.0006921223,0.00213096,0.000005600352,0.00003583889,0.00009603843,0.000040675,0.002779156,0.989688,0.00005868338,0.00439943,0.00000466688],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937243,0.001589329,0.001833882,0.0002394095,0.00007366836,0.00004043736,0.000288658,0.00006901441,0.002141347],"genre_scores_gemma":[0.9943576,0.0008781218,0.001433922,0.00005944435,0.000008501391,0.00003512737,0.0003683469,0.00001084075,0.002848055],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004711844,"threshold_uncertainty_score":0.009368837,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0107362435557531,"score_gpt":0.2828472228495921,"score_spread":0.272110979293839,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}