{"id":"W2759286145","doi":"10.1016/j.clim.2017.09.021","title":"Circulating B cells in type 1 diabetics exhibit fewer maturation-associated phenotypes","year":2017,"lang":"en","type":"article","venue":"Clinical Immunology","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; Juvenile Diabetes Research Foundation United States of America; University of Pennsylvania","keywords":"Immunophenotyping; Phenotype; Biology; B cell; Immunology; Autoantibody; Autoimmunity; Cell type; Transmembrane protein; Receptor; Cell; Antibody; Antigen; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002917731,0.0003071876,0.0002935583,0.001160495,0.0003021683,0.0004735428,0.0001749069,0.0002583363,0.003017805],"category_scores_gemma":[0.0006903184,0.0001619125,0.0001386935,0.0005501629,0.0002254378,0.0002098887,0.0002374629,0.0004459964,0.0003474263],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001387275,"about_ca_system_score_gemma":0.00007566324,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008843641,"about_ca_topic_score_gemma":0.0005830851,"domain_scores_codex":[0.9998425,0.0000266331,0.00002334753,0.0000548045,0.00003029332,0.00002240506],"domain_scores_gemma":[0.9996301,0.00006101885,0.000149317,0.00002878396,0.00003909761,0.00009165669],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003401947,0.0003074345,0.6131183,0.0002670291,0.0001336249,0.001952465,0.0008385064,0.0001930385,0.3200568,0.0002368317,0.0006090199,0.05888503],"study_design_scores_gemma":[0.00004688606,0.0006991967,0.9837835,0.00002524712,0.00009079777,0.004737905,0.0002880579,0.0002178241,0.008851944,0.0001862022,0.001063285,0.000009063602],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981584,0.0008422466,0.0002289213,0.00003105904,0.000009127695,0.000003804583,0.0001331518,0.00001806289,0.0005751636],"genre_scores_gemma":[0.998503,0.0003449139,0.0003574995,0.00004027977,0.00001832401,0.000004725965,0.0002453567,0.00001153041,0.0004743008],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003017805,"threshold_uncertainty_score":0.0100956,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02402854674912694,"score_gpt":0.3156138372902007,"score_spread":0.2915852905410737,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}