{"id":"W2759397991","doi":"10.3324/haematol.2017.170928","title":"CD56 <sup>bright</sup> natural killer regulatory cells in filgrastim primed donor blood or marrow products regulate chronic graft- <i>versus</i> -host disease: the Canadian Blood and Marrow Transplant Group randomized 0601 study results","year":2017,"lang":"en","type":"article","venue":"Haematologica","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nova Scotia Health Authority; Vancouver General Hospital; Princess Margaret Cancer Centre; BC Cancer Agency; McMaster University; Hospital for Sick Children; Université de Montréal; Hôpital Maisonneuve-Rosemont; University of Toronto; Dalhousie University; Hamilton Health Sciences; BC Children's Hospital; CancerCare Manitoba; Health Sciences Centre; University of British Columbia","funders":"National Cancer Institute","keywords":"Filgrastim; Immunology; Bone marrow; Medicine; Apheresis; Graft-versus-host disease; Myeloid; Immune system; Natural killer cell; Granulocyte colony-stimulating factor; Transplantation; Cytotoxic T cell; Internal medicine; Biology; Chemotherapy; Platelet","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00192191,0.0007079734,0.001679114,0.0002778664,0.001026005,0.0002270486,0.0006562958,0.000321763,0.0001313828],"category_scores_gemma":[0.0006816298,0.0004166897,0.0002297492,0.0002764425,0.0009573876,0.0002283005,0.00007522513,0.0007027916,0.00003108864],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001500504,"about_ca_system_score_gemma":0.0008068893,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.008842858,"about_ca_topic_score_gemma":0.08070744,"domain_scores_codex":[0.9949045,0.0007843979,0.001208969,0.001312006,0.0007408489,0.001049245],"domain_scores_gemma":[0.9959207,0.0008834699,0.0004943723,0.001861409,0.0001602285,0.00067984],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8020929,0.006196841,0.0571336,0.008756151,0.00651447,0.06766206,0.02236261,0.0001695342,0.01644907,0.003938026,0.007581813,0.001142906],"study_design_scores_gemma":[0.7130709,0.001798302,0.2475235,0.003424953,0.009272994,0.003310352,0.001020695,0.001920777,0.01452329,0.0002238585,0.001852608,0.00205782],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9836069,0.0018439,0.00000388996,0.005029884,0.0005909963,0.007714008,0.0001432285,0.0001388668,0.000928361],"genre_scores_gemma":[0.9964192,0.0004583074,0.0003910308,0.0001729575,0.0001608344,0.0004913774,0.0002100201,0.00007187085,0.001624393],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1903899,"threshold_uncertainty_score":0.9998285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01780965336070113,"score_gpt":0.2470077474114737,"score_spread":0.2291980940507725,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}