{"id":"W2759433538","doi":"10.1038/nrdp.2017.65","title":"Fragile X syndrome","year":2017,"lang":"en","type":"review","venue":"Nature Reviews Disease Primers","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":779,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","keywords":"Fragile X syndrome; FMR1; Autism spectrum disorder; Autism; Intellectual disability; Neuroscience; Anxiety; Impulsivity; Psychology; Gene silencing; Medicine; Psychiatry; Fragile x; Genetics; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003594391,0.0009954395,0.0008471943,0.001351744,0.0002572761,0.0007987299,0.0009050537,0.001042464,0.008532947],"category_scores_gemma":[0.0007460098,0.0002159105,0.0003107373,0.0008401281,0.0004935756,0.0007548979,0.0009520045,0.001709667,0.00424771],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000524906,"about_ca_system_score_gemma":0.0006767465,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001256153,"about_ca_topic_score_gemma":0.002801059,"domain_scores_codex":[0.9998513,0.00002084671,0.0000164912,0.00003249151,0.00005927573,0.00001964913],"domain_scores_gemma":[0.9998713,0.00005031668,0.00002039642,0.000008634578,0.0000267995,0.00002262036],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003589977,0.0000137072,0.0001442142,0.001426163,0.0000365849,0.000420416,0.00002314614,0.00009138985,0.0007960556,0.003385437,0.1136186,0.8800083],"study_design_scores_gemma":[0.00001098945,0.00001452246,0.0005024016,0.001132271,0.00004428679,0.002954374,0.0000170671,0.00002386044,0.0003115634,0.001398483,0.9935817,0.000008579796],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002190757,0.9858803,0.0008086495,0.001460068,0.002490144,0.00001178203,0.0001113729,0.00006367045,0.008955027],"genre_scores_gemma":[0.002502512,0.9803477,0.0008948424,0.001944738,0.002240992,0.00002387498,0.0003554368,0.00001103856,0.01167887],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.008532947,"threshold_uncertainty_score":0.02854556,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04772420476556542,"score_gpt":0.3697148473623214,"score_spread":0.321990642596756,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}