{"id":"W2759588691","doi":"10.1161/res.113.suppl_1.a318","title":"Abstract 318: Dynamic Mass Redistribution Analysis Of Endogenous β-adrenergic Receptor Signaling In Cardiac Cells","year":2013,"lang":"en","type":"article","venue":"Circulation Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Stimulation; Endogeny; Endocrinology; Receptor; Internal medicine; Agonist; Cholera toxin; Chemistry; Propranolol; Signal transduction; Adrenergic receptor; Biology; Cell biology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001253974,0.0001150499,0.0002612898,0.0004270677,0.00009085662,0.00004765841,0.0001743053,0.0002044771,0.000704301],"category_scores_gemma":[0.00009351764,0.0001202975,0.0001983105,0.000958205,0.00005907676,0.00001178632,0.0000451794,0.000174996,0.00002839459],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009315798,"about_ca_system_score_gemma":0.00009074635,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003609553,"about_ca_topic_score_gemma":0.00001851529,"domain_scores_codex":[0.9981998,0.0002334103,0.0003980539,0.0003763199,0.0004340994,0.0003583625],"domain_scores_gemma":[0.9990024,0.00005130405,0.0001076473,0.0003215125,0.0004293141,0.00008782082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001475111,0.00003448431,0.002880944,0.00002105347,0.0001589363,8.025199e-7,0.00004986659,0.0348707,0.9609465,0.00006192165,0.00004699744,0.0009130258],"study_design_scores_gemma":[0.0002007051,0.00005536165,0.01585016,0.00001827625,0.00004179002,2.515686e-7,0.0002918207,0.0137459,0.9693237,0.0002321909,0.00008830636,0.0001515565],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948514,0.0004569485,0.003707682,0.00002716308,0.0001008679,0.000334175,0.00005156541,0.000007211676,0.0004630112],"genre_scores_gemma":[0.9984985,0.00009144252,0.0002834141,0.00000491133,0.00006297497,0.00005388413,0.0009398735,0.00001622313,0.00004879941],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02112479,"threshold_uncertainty_score":0.7711602,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03653471968610693,"score_gpt":0.3034051416121067,"score_spread":0.2668704219259998,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}