{"id":"W2760024633","doi":"10.1002/bit.26459","title":"Engineering of cell membrane to enhance heterologous production of hyaluronic acid in <i>Bacillus subtilis</i>","year":2017,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Bacillus subtilis; Biochemistry; Hyaluronan synthase; Chemistry; Phosphatidylethanolamine; Membrane; Microbiology; Biology; Bacteria; Enzyme; Phospholipid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001685145,0.0001060999,0.0001590953,0.0001697996,0.0000357025,0.000006474217,0.0002189928,0.0002473332,0.000002615767],"category_scores_gemma":[0.0001528057,0.0001078116,0.00002827212,0.00008750273,0.00009363521,0.000006563773,0.0001723235,0.0001277514,0.000001458414],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008093687,"about_ca_system_score_gemma":0.00001515999,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001954365,"about_ca_topic_score_gemma":0.00003742135,"domain_scores_codex":[0.9992901,0.000007798025,0.0001803708,0.0002590045,0.00006592487,0.0001967743],"domain_scores_gemma":[0.9994237,0.000003448608,0.00006502886,0.0004382171,0.00003445763,0.00003513794],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005005385,0.00002391474,0.0005320392,0.0001068894,0.00001038395,0.000001916888,0.00001515684,0.0007242986,0.995656,0.00003215082,0.000004752743,0.002842429],"study_design_scores_gemma":[0.0001734931,0.0002382269,0.002142478,0.00002995957,0.000003087379,0.00000837866,0.000009834315,0.0004658695,0.9957961,0.000002759235,0.001035993,0.00009386073],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975539,0.0005418762,0.001193981,0.0003601798,0.0001085979,0.000188359,0.000004784653,0.00001529219,0.00003304062],"genre_scores_gemma":[0.9981713,0.0002821558,0.001410756,0.000006283149,0.00002450577,0.00001511607,0.000004647345,0.00001047689,0.00007477078],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002748569,"threshold_uncertainty_score":0.4396428,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006095972774832055,"score_gpt":0.2404338098052488,"score_spread":0.2343378370304167,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}