{"id":"W2760214433","doi":"10.1038/bcj.2017.86","title":"Meis2 as a critical player in MN1-induced leukemia","year":2017,"lang":"en","type":"article","venue":"Blood Cancer Journal","topic":"Protein Degradation and Inhibitors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"BC Cancer Agency; Canadian Institutes of Health Research; Deutsche Krebshilfe; University of British Columbia; BC Cancer Foundation; Vetenskapsrådet; Provincial Health Services Authority; Deutsche Forschungsgemeinschaft; Terry Fox Foundation; Genome British Columbia","keywords":"Biology; Myeloid leukemia; Cancer research; Leukemia; Myeloid; Progenitor cell; Phenotype; Hox gene; Stem cell; Gene expression profiling; Immunology; Genetics; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002038446,0.0001077427,0.0001135642,0.00003969801,0.0002708648,0.0001572602,0.0003045871,0.000135124,0.0001845673],"category_scores_gemma":[0.000393829,0.00009742728,0.00007344384,0.00002190246,0.00005832309,0.0000149269,0.00008250759,0.0002635185,0.00001492648],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004034964,"about_ca_system_score_gemma":0.0004310324,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001328426,"about_ca_topic_score_gemma":0.0001678851,"domain_scores_codex":[0.9991773,0.00004279102,0.0001961854,0.0001864967,0.0001567431,0.000240521],"domain_scores_gemma":[0.9993814,0.000005510422,0.0001065721,0.0002864683,0.00007949503,0.0001405116],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001435811,0.0001121201,0.01593614,0.00001426395,0.00008308461,0.0001236319,0.00006189568,0.000009750724,0.9598745,0.0004444517,0.008098914,0.01509773],"study_design_scores_gemma":[0.002160373,0.0002739948,0.01068187,0.00009605427,0.0000326711,0.0003427006,0.00003761305,0.00003004315,0.9508703,0.0004661009,0.03476296,0.0002452708],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921797,0.0009839624,0.00004526768,0.001787542,0.0005930157,0.00006769239,0.000004858959,0.00000419882,0.004333798],"genre_scores_gemma":[0.9970483,0.0003920598,0.000221624,0.0005431249,0.001149505,0.00001838378,0.00000249297,0.00001449177,0.0006100651],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02666405,"threshold_uncertainty_score":0.3972969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02087468825402057,"score_gpt":0.342248153853548,"score_spread":0.3213734655995275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}