{"id":"W2760458695","doi":"10.1084/jem.20171129","title":"ICAMs support B cell interactions with T follicular helper cells and promote clonal selection","year":2017,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":98,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Horizon 2020 Framework Programme; Benoziyo Endowment Fund for the Advancement of Science; Irma und Jacques Ber-Lehmsdorf - Stiftung; Azrieli Foundation; Human Frontier Science Program; H2020 European Research Council; Rising Tide Foundation; Gerald O. Mann Charitable Foundation","keywords":"Germinal center; B cell; Biology; Antigen; Cell biology; Naive B cell; Affinity maturation; CD40; Cell; Antigen presentation; Immune system; Antibody; T cell; Immunology; Antigen-presenting cell; Cytotoxic T cell; In vitro; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001017606,0.0002759008,0.00016708,0.000243343,0.0002495157,0.0003823539,0.0002044301,0.0003561194,0.002301797],"category_scores_gemma":[0.0001565711,0.0001416428,0.0001756851,0.00009119706,0.0001366557,0.0002269161,0.0003249804,0.0007084693,0.0006480567],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002226718,"about_ca_system_score_gemma":0.000185597,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006184098,"about_ca_topic_score_gemma":0.001039701,"domain_scores_codex":[0.9997945,0.00003186624,0.000005823814,0.0000201821,0.00005016004,0.00009736499],"domain_scores_gemma":[0.9998435,0.00003446828,0.00002733774,0.00001396435,0.00002013374,0.00006066936],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002352053,0.00002007224,0.0002872832,0.00001382396,0.000002403037,0.00002973923,0.00001477042,0.00002765105,0.9981523,0.0001803553,0.00005171431,0.001196291],"study_design_scores_gemma":[0.00002950152,0.0002435445,0.01472838,0.00001436202,0.00002337005,0.0003336555,0.00008180055,0.002138888,0.9762537,0.0002220598,0.005923887,0.000006901932],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927651,0.001148921,0.002624584,0.00009360022,0.00002150989,0.00001513135,0.00008280761,0.00006772445,0.003180607],"genre_scores_gemma":[0.9968603,0.000275637,0.001735475,0.00003679799,0.00001998212,0.00001248463,0.0001102425,0.00001383443,0.0009351818],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002301797,"threshold_uncertainty_score":0.007700205,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01271251996278554,"score_gpt":0.2675653130590349,"score_spread":0.2548527930962494,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}