{"id":"W2760562204","doi":"10.1042/bsr20171061","title":"Dual roles of parathyroid hormone related protein in TGF-β1 signaling and fibronectin up-regulation in mesangial cells","year":2017,"lang":"en","type":"article","venue":"Bioscience Reports","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Wuhan University; National Natural Science Foundation of China","keywords":"Fibronectin; Parathyroid hormone; Transforming growth factor; Hormone; Internal medicine; Endocrinology; Signal transduction; Cell biology; Chemistry; Biology; Medicine; Calcium; Extracellular matrix","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005772618,0.0001186703,0.000152714,0.00008540246,0.0001089014,0.00004671169,0.0001236126,0.0001317588,0.000003590718],"category_scores_gemma":[0.0004043499,0.000116452,0.0000359241,0.00008951019,0.0002392321,0.00002080602,0.0001268751,0.00006075154,5.452296e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001644966,"about_ca_system_score_gemma":0.0001472988,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008532741,"about_ca_topic_score_gemma":0.00007258414,"domain_scores_codex":[0.9986843,0.00004635338,0.0004174569,0.0004425928,0.0001975595,0.0002117369],"domain_scores_gemma":[0.9990458,0.00000888119,0.0004162309,0.0004229579,0.0000435033,0.00006258365],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004190539,0.00004842439,0.008567188,0.000010239,0.000003169404,0.00004121071,0.0001153815,0.0002110307,0.9904702,0.000005970073,0.00002192166,0.0004634011],"study_design_scores_gemma":[0.0002574848,0.00009425706,0.1459834,0.00005211173,0.000003834078,0.00002507188,0.00004692217,0.0001413079,0.8530688,0.0001102164,0.00009055304,0.0001259756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998719,0.0007798919,0.00003826104,0.00003011679,0.00006831052,0.0002650118,0.000003224323,0.000007292732,0.00008890007],"genre_scores_gemma":[0.9993844,0.00001357773,0.0004000748,0.00000400418,0.00003318359,0.00001500772,0.00001075063,0.000009223203,0.0001297957],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1374162,"threshold_uncertainty_score":0.4748774,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008934780654530322,"score_gpt":0.2499395528217662,"score_spread":0.2410047721672358,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}