{"id":"W2760923115","doi":"10.1016/j.clinthera.2017.09.006","title":"Enrollment of Neonates in More Than One Clinical Trial","year":2017,"lang":"en","type":"review","venue":"Clinical Therapeutics","topic":"Pharmaceutical studies and practices","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"Health Canada; National Institutes of Health","keywords":"Medicine; Observational study; Clinical trial; Population; Intensive care medicine; Pediatrics; Legislature; Family medicine; Environmental health; Internal medicine; Law","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00551115,0.0005004832,0.00615098,0.00009177818,0.00008413028,0.00003225735,0.0006249812,0.001143178,0.0001311935],"category_scores_gemma":[0.002561574,0.0003296771,0.002352478,0.000164059,0.0008689794,0.00005784752,0.0003457447,0.002618973,0.0000671005],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006165288,"about_ca_system_score_gemma":0.0005472521,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001328059,"about_ca_topic_score_gemma":0.000006799501,"domain_scores_codex":[0.9929819,0.001149605,0.004213357,0.0006882949,0.0005130542,0.0004537893],"domain_scores_gemma":[0.9875071,0.008782,0.002121681,0.001148865,0.000129764,0.0003105962],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.009030008,0.002712096,0.0009738918,0.00323467,0.002292659,0.00004461019,0.00001895777,2.534055e-8,2.909863e-8,0.0000608324,0.00009494857,0.9815373],"study_design_scores_gemma":[0.02583913,0.00226369,0.0005403908,0.006468027,0.005714169,0.000007640854,0.00001480968,0.00001479616,2.689585e-7,0.0001325521,0.9587192,0.0002853256],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002757361,0.9915141,0.000005075227,0.001512631,0.001955369,0.002164731,0.00003546636,0.00002674476,0.002510153],"genre_scores_gemma":[0.000253636,0.9954699,0.0003513673,0.001202462,0.002084284,0.00006525504,0.00003611483,0.00006357378,0.0004733732],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.981252,"threshold_uncertainty_score":0.9999155,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.8577238101874483,"score_gpt":0.6899087037792202,"score_spread":0.1678151064082281,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}