{"id":"W2760971775","doi":"10.1038/s41467-017-01183-2","title":"Evolutionary genetics of immunological supertypes reveals two faces of the Red Queen","year":2017,"lang":"en","type":"article","venue":"Nature Communications","topic":"Evolution and Genetic Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"Fisheries and Oceans Canada; McGill University; University of British Columbia; Canada's Michael Smith Genome Sciences Centre; Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Directorate for Biological Sciences; Biotechnology and Biological Sciences Research Council; British Ecological Society; Leverhulme Trust; Ecological Society of America","keywords":"Biology; Evolutionary biology; Allele; Major histocompatibility complex; Genetics; Convergent evolution; Gene; Phylogenetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001339516,0.00007899215,0.0001142799,0.00001784145,0.0003132364,0.000008340851,0.001869223,0.0002427046,0.000007903368],"category_scores_gemma":[0.000413881,0.00005776224,0.0001016256,0.00004788492,0.0006148347,0.000002921921,0.0009461034,0.0002442871,0.000001103564],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008711446,"about_ca_system_score_gemma":0.00006904957,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003521743,"about_ca_topic_score_gemma":0.0002354642,"domain_scores_codex":[0.9993395,0.0001320658,0.000210982,0.0001204127,0.0001042774,0.00009276089],"domain_scores_gemma":[0.9966203,0.00002929154,0.0002278734,0.002860651,0.0002406687,0.00002121956],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00004282344,0.0002478367,0.2004777,0.00001693796,0.0001450026,9.663761e-8,0.00006898365,0.000206219,0.7752953,0.01393845,0.00773814,0.001822488],"study_design_scores_gemma":[0.0003976332,0.00008011927,0.9268638,0.00002709557,0.0000373197,0.00000525974,0.00007886467,0.0005468267,0.02249747,0.001490262,0.04784591,0.0001294291],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9519654,0.03036665,0.0001688834,0.008041082,0.0002381328,0.0003314282,0.000162878,0.00001127837,0.008714298],"genre_scores_gemma":[0.9900818,0.003335417,0.005822406,0.00009081675,0.00002444592,0.000008487559,0.00007603443,0.000007097087,0.0005534989],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7527978,"threshold_uncertainty_score":0.3473512,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01672935503832087,"score_gpt":0.3161887759787865,"score_spread":0.2994594209404656,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}