{"id":"W2761016513","doi":"10.1161/hypertensionaha.117.10156","title":"Apelin Is a Negative Regulator of Angiotensin II–Mediated Adverse Myocardial Remodeling and Dysfunction","year":2017,"lang":"en","type":"article","venue":"Hypertension","topic":"Apelin-related biomedical research","field":"Medicine","cited_by":108,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Shanghai Jiao Tong University; Canada Research Chairs; National Institutes of Health; University of Alberta","keywords":"Apelin; Internal medicine; Angiotensin II; Endocrinology; Protein kinase B; Nitric oxide synthase; Fibrosis; Medicine; Nitric oxide; Chemistry; Signal transduction; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001925764,0.0003093698,0.0002413697,0.0002234487,0.0001350421,0.000276676,0.0001574574,0.0002119397,0.0006356103],"category_scores_gemma":[0.0001894042,0.00009965283,0.0001665085,0.0001182106,0.0001844988,0.0001314471,0.0002567099,0.000417656,0.0001836822],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001235868,"about_ca_system_score_gemma":0.0001131644,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001407499,"about_ca_topic_score_gemma":0.0001392551,"domain_scores_codex":[0.9998904,0.0000224681,0.00001085666,0.00001976904,0.00003891989,0.00001746312],"domain_scores_gemma":[0.9998248,0.00001662057,0.0000759466,0.00001322923,0.00001629301,0.00005305078],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008567032,0.00004100867,0.004146849,0.0001132457,0.00004453899,0.001091831,0.00003111467,0.0000928661,0.9825656,0.0001413611,0.0001901986,0.01068469],"study_design_scores_gemma":[0.0003018436,0.00348539,0.4829172,0.0000894825,0.0003171709,0.01789832,0.0002257068,0.003588886,0.4739081,0.001388932,0.01582864,0.00005023316],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921846,0.00402812,0.001870346,0.0001543941,0.00003756165,0.00001316161,0.0001582464,0.00006842564,0.001485077],"genre_scores_gemma":[0.9945706,0.002574897,0.001011625,0.0001083677,0.00003999716,0.00002538096,0.0002009292,0.00001073458,0.001457656],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006356103,"threshold_uncertainty_score":0.002126396,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03986779698073521,"score_gpt":0.2912923988536238,"score_spread":0.2514246018728886,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}