{"id":"W2761109864","doi":"10.1038/s41598-017-13888-x","title":"Abnormal M1/M2 macrophage phenotype profiles in the small airway wall and lumen in smokers and chronic obstructive pulmonary disease (COPD)","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":175,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"National Medical Research Council; National Health and Medical Research Council","keywords":"COPD; Medicine; Bronchoalveolar lavage; CD163; Cytokine; Pathogenesis; Macrophage; Pathology; Immunology; Airway; Lung; Proinflammatory cytokine; Phenotype; Inflammation; Internal medicine; Biology; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003122206,0.0002134894,0.0002237491,0.0006405343,0.0002351966,0.0002454048,0.00008581748,0.0003629932,0.0008572033],"category_scores_gemma":[0.0001687842,0.0001466118,0.0001439636,0.0001775923,0.0002436153,0.0001896588,0.0002385019,0.0002137479,0.0002282898],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000666968,"about_ca_system_score_gemma":0.0000998805,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002558803,"about_ca_topic_score_gemma":0.0004162349,"domain_scores_codex":[0.9998833,0.00003023274,0.0000123478,0.0000261145,0.00002380917,0.00002414257],"domain_scores_gemma":[0.9999224,0.00001175652,0.00001985114,0.000006886867,0.00001396954,0.00002512216],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000891912,0.0001501946,0.1142596,0.00009532469,0.0000179002,0.0006136664,0.0003555795,0.00002638336,0.878308,0.00005931304,0.00004219358,0.005179872],"study_design_scores_gemma":[0.00002446936,0.001265572,0.9295523,0.00002131754,0.00005983489,0.005325194,0.0005428251,0.0003445951,0.06173268,0.0002090718,0.0009125824,0.00000963301],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984775,0.001045838,0.0002022731,0.0000130764,0.000003369417,0.000009702141,0.00003611606,0.00000416204,0.0002079002],"genre_scores_gemma":[0.9988301,0.0003664364,0.0003404982,0.00002511799,0.000008056978,0.00001938911,0.00009075995,0.000002546948,0.0003170055],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008572033,"threshold_uncertainty_score":0.002867639,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01847431895705197,"score_gpt":0.2779349718197415,"score_spread":0.2594606528626895,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}