{"id":"W2761174687","doi":"10.1128/mbio.01323-17","title":"<i>Entamoeba histolytica</i> -Induced Mucin Exocytosis Is Mediated by VAMP8 and Is Critical in Mucosal Innate Host Defense","year":2017,"lang":"en","type":"article","venue":"mBio","topic":"Amoebic Infections and Treatments","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University of Calgary","funders":"Canadian Institutes of Health Research; Crohn's and Colitis Canada; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Entamoeba histolytica; Mucin; Innate immune system; Exocytosis; Cell biology; Host (biology); Immunology; Biology; Lytic cycle; Microbiology; Immune system; Genetics; Virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009913874,0.0002947559,0.000170372,0.0001329988,0.0001313544,0.0003063792,0.0001241164,0.0002556703,0.001015338],"category_scores_gemma":[0.00009038789,0.0000859014,0.0002079933,0.00009184935,0.000162208,0.0001922872,0.0002430173,0.0003377346,0.0003285251],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002022594,"about_ca_system_score_gemma":0.00007294916,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001467038,"about_ca_topic_score_gemma":0.000118355,"domain_scores_codex":[0.999893,0.00001690418,0.00001126087,0.00002264122,0.00002216787,0.00003417673],"domain_scores_gemma":[0.9999348,0.000007263015,0.00002773495,0.000007033871,0.00001016702,0.0000129835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009767914,0.000005761055,0.0003663275,0.00003128925,0.000002564756,0.00009930673,0.000005483927,0.00001208533,0.998849,0.00002703705,0.00002991347,0.0004734211],"study_design_scores_gemma":[0.0000175227,0.0003244361,0.03514023,0.00002119333,0.00001788965,0.001793839,0.00008556142,0.0007574386,0.9580709,0.000108628,0.003656607,0.000005707868],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936799,0.002563587,0.002187066,0.0001385994,0.00004071929,0.0000209114,0.0003455723,0.00008304865,0.0009406885],"genre_scores_gemma":[0.9962256,0.0008194891,0.001116771,0.00004272789,0.00001681308,0.00002404565,0.0004249524,0.000009132592,0.001320319],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001015338,"threshold_uncertainty_score":0.00339663,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0235568206057652,"score_gpt":0.3084827526004667,"score_spread":0.2849259319947015,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}