{"id":"W2761230962","doi":"10.1016/j.jacc.2017.07.102","title":"GW28-e0806 Pyr1-Apelin 13 is a negative modulator of angiotensin II-mediated adverse myocardial hypertrophy, remodeling and fibrosis","year":2017,"lang":"en","type":"article","venue":"Journal of the American College of Cardiology","topic":"Apelin-related biomedical research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Apelin; Medicine; Angiotensin II receptor type 1; Angiotensin II; Fibrosis; Blood pressure; Receptor; Internal medicine; Muscle hypertrophy; Renin–angiotensin system; Endocrinology; Angiotensin receptor; Cardiology; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002709804,0.0004410673,0.0006064718,0.0001814127,0.0002168769,0.0002622711,0.0002893738,0.0005494308,0.003312791],"category_scores_gemma":[0.000218608,0.000213643,0.0004496183,0.0001517269,0.0003150525,0.0002136898,0.0003885131,0.001225102,0.0006802259],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001449606,"about_ca_system_score_gemma":0.0002869312,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004182718,"about_ca_topic_score_gemma":0.0006682309,"domain_scores_codex":[0.9998289,0.00004562713,0.00001600271,0.00003563986,0.000026539,0.00004725902],"domain_scores_gemma":[0.9998646,0.00001537148,0.00004249468,0.00001388809,0.00000797984,0.00005559683],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02417719,0.0007766429,0.004349019,0.0003184878,0.0004806533,0.00107974,0.00004650077,0.0003331419,0.9470531,0.0006334031,0.001517897,0.01923416],"study_design_scores_gemma":[0.01782572,0.03017445,0.3620873,0.000191613,0.002545899,0.008387222,0.000650735,0.009791956,0.5263633,0.003084255,0.03867972,0.0002178158],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924237,0.001309284,0.002278016,0.000559675,0.0002433334,0.00005421286,0.0009012611,0.000169235,0.002061398],"genre_scores_gemma":[0.9929287,0.0008564784,0.001253638,0.0004087572,0.00006513188,0.0001011951,0.001032015,0.00003843562,0.003315671],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003312791,"threshold_uncertainty_score":0.01108241,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01824480954967322,"score_gpt":0.292172488766444,"score_spread":0.2739276792167708,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}