{"id":"W2761236690","doi":"10.1182/blood-2017-07-731588","title":"FCR achieves long-term durable remissions in patients with IGHV-mutated CLL","year":2017,"lang":"en","type":"review","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Impact","funders":"","keywords":"IGHV@; Chemoimmunotherapy; Fludarabine; Chronic lymphocytic leukemia; Rituximab; Medicine; Internal medicine; Cyclophosphamide; Oncology; Alemtuzumab; Progression-free survival; Leukemia; Immunology; Chemotherapy; Transplantation; Lymphoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003294416,0.0005540455,0.002136751,0.0003759954,0.0001583099,0.00008721243,0.0006585649,0.0005233294,0.0002504775],"category_scores_gemma":[0.0004876476,0.0003550975,0.0002795403,0.0003585131,0.0001754629,0.0001075926,0.0002823817,0.0009808356,0.0003415827],"about_ca_system_candidate":true,"about_ca_system_consensus":true,"about_ca_system_score_codex":0.00414749,"about_ca_system_score_gemma":0.01357859,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001468577,"about_ca_topic_score_gemma":0.0000630103,"domain_scores_codex":[0.9967319,0.0001540682,0.0007048636,0.0007530837,0.0008853702,0.0007707431],"domain_scores_gemma":[0.9970977,0.0001786287,0.0004180103,0.001719343,0.0001650053,0.0004213331],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004762716,0.007081917,0.02562386,0.08756693,0.00179443,0.005852062,0.0001173652,2.976151e-7,0.000001344551,0.00001078682,0.001450119,0.8700246],"study_design_scores_gemma":[0.1281679,0.001414767,0.02558431,0.1839458,0.007134102,0.001236709,0.000006374969,0.000008118092,0.00002672712,0.000008571841,0.6509172,0.001549362],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01990806,0.9738628,7.482639e-7,0.00002683761,0.0001095714,0.002595285,0.00006075613,0.00008146273,0.003354452],"genre_scores_gemma":[0.001248914,0.9895005,0.0001152897,0.00001748694,0.0001737588,0.0001653892,0.0008674305,0.0001572146,0.007754026],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8684753,"threshold_uncertainty_score":0.9998901,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06436159046231887,"score_gpt":0.3778367711414914,"score_spread":0.3134751806791726,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}