{"id":"W2761239970","doi":"10.1136/bmjopen-2017-017863","title":"A multicentre randomised controlled trial assessing whether MRI-targeted biopsy is non-inferior to standard transrectal ultrasound guided biopsy for the diagnosis of clinically significant prostate cancer in men without prior biopsy: a study protocol","year":2017,"lang":"en","type":"article","venue":"BMJ Open","topic":"Prostate Cancer Diagnosis and Treatment","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Hospital","funders":"National Institute for Health and Care Research","keywords":"Medicine; Biopsy; Prostate cancer; Rectal examination; Prostate biopsy; Radiology; Prostate; Cancer; Prostate-specific antigen; Ultrasound; Urology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01002602,0.004658415,0.008748154,0.001221779,0.0009633665,0.002711684,0.003028569,0.005534811,0.0192067],"category_scores_gemma":[0.0161841,0.001479909,0.0056323,0.001153731,0.002505424,0.00226507,0.001435352,0.003865005,0.0019334],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002455234,"about_ca_system_score_gemma":0.004392589,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00187492,"about_ca_topic_score_gemma":0.002614048,"domain_scores_codex":[0.9909237,0.006434981,0.0006022796,0.0008773576,0.0004905196,0.0006711715],"domain_scores_gemma":[0.9927973,0.003339856,0.001679231,0.0005471939,0.0006251043,0.001011229],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9919585,0.001892808,0.0001201909,0.001812555,0.001278538,0.0000317139,0.00003757459,0.0002527143,0.0002793157,0.0001268209,0.0003565335,0.001852798],"study_design_scores_gemma":[0.9847769,0.01372515,0.0002093461,0.00007564202,0.0005439773,0.000008505704,0.0000133604,0.0002151122,0.00004757439,0.0001333076,0.0002406006,0.00001055511],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"protocol","genre_scores_codex":[0.598623,0.01200004,0.006105822,0.00284205,0.006029941,0.3621894,0.004550887,0.0006420038,0.007016825],"genre_scores_gemma":[0.5069126,0.003427048,0.01038845,0.002699854,0.001063716,0.4667099,0.001468192,0.00005963874,0.007270562],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.0192067,"threshold_uncertainty_score":0.06425279,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08139295102434736,"score_gpt":0.4740560701718871,"score_spread":0.3926631191475397,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}