{"id":"W2761338549","doi":"10.1016/j.exger.2017.10.010","title":"DNA methylation patterns are related to co-morbidity status and circulating C-reactive protein levels in the nursing home elderly","year":2017,"lang":"en","type":"article","venue":"Experimental Gerontology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"Impact; University of British Columbia; BC Children's Hospital; McMaster University","funders":"Canadian Institutes of Health Research","keywords":"DNA methylation; Immune system; Immunology; Biomarker; Immunosenescence; Inflammation; Methylation; Medicine; C-reactive protein; Peripheral blood mononuclear cell; Dementia; Pathological; Disease; Biology; Internal medicine; Gene; Genetics; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002573586,0.0001462105,0.0001600709,0.00004063356,0.0002608063,0.00006686023,0.0001573577,0.0001626446,0.00001269998],"category_scores_gemma":[0.00008484197,0.0001306059,0.00003512415,0.00002416932,0.00009963353,0.00001473849,0.00005504067,0.0001107149,0.000002841048],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005519654,"about_ca_system_score_gemma":0.00002242923,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003032304,"about_ca_topic_score_gemma":0.0002357857,"domain_scores_codex":[0.998852,0.0001963716,0.0002111796,0.0003600664,0.0001098275,0.0002706192],"domain_scores_gemma":[0.9993267,0.00001840405,0.0001923476,0.0003709174,0.00002782417,0.00006381978],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003897387,0.00007115337,0.05578949,0.000003784747,0.00001414365,0.000005197132,0.002330068,0.000008889058,0.9371327,0.000105314,0.0000046869,0.004495583],"study_design_scores_gemma":[0.0004331961,0.0002667528,0.4658106,0.00002101559,0.000003693128,0.0000047381,0.00141379,0.000022701,0.5315804,0.0002221232,0.00009956666,0.0001214429],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965401,0.001089538,0.0004795489,0.0002424029,0.0001213811,0.0004806682,0.00001502139,0.000006432394,0.001024883],"genre_scores_gemma":[0.9994659,0.000006435677,0.0002691132,0.00004167125,0.00005703136,0.00006374135,0.00004399804,0.00001519063,0.00003690024],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4100211,"threshold_uncertainty_score":0.5325953,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05488787597699329,"score_gpt":0.3751203449443801,"score_spread":0.3202324689673868,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}