{"id":"W2761460062","doi":"10.2174/1874467209999160114145952","title":"Editorial (Thematic Issue: New Insights into a Classical Pathway: Key Roles of the Mevalonate Cascade in Different Diseases (Part I))","year":2016,"lang":"en","type":"editorial","venue":"Current Molecular Pharmacology","topic":"Plant biochemistry and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; University of Toronto; SickKids Foundation; University of Manitoba","funders":"National Heart, Lung, and Blood Institute","keywords":"Key (lock); Cascade; Computational biology; Data science; Neuroscience; Biology; Computer science; Chemistry; Computer security","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0001662903,0.0007675849,0.00090536,0.0001157854,0.00008723849,0.00002620079,0.001258055,0.00139395,0.00005913033],"category_scores_gemma":[0.0007486682,0.0004875872,0.0005757065,0.0001647758,0.0003774118,0.00000741971,0.0007515282,0.0008323735,0.0000199459],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001194225,"about_ca_system_score_gemma":0.00102917,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007786929,"about_ca_topic_score_gemma":0.00003453507,"domain_scores_codex":[0.9961377,0.0005849219,0.0008088959,0.001022068,0.0008521411,0.0005942323],"domain_scores_gemma":[0.9980356,0.0002341066,0.0005761425,0.0006786271,0.0001922047,0.0002833856],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002815275,0.0002877907,0.000007728463,0.0002439775,0.0001691971,0.00001038201,0.00003069557,0.000001836981,0.4458258,0.000004633685,0.5516458,0.001490642],"study_design_scores_gemma":[0.001117927,0.00008189955,0.000003415553,0.000271343,0.0002312969,0.000001696534,0.000003910008,0.000006170842,0.4427333,0.0001175055,0.5551037,0.0003278071],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"editorial","genre_scores_codex":[0.04651928,0.01012963,0.00005312044,0.0003896791,0.941656,0.0006224448,0.0005172326,0.0000221055,0.00009052642],"genre_scores_gemma":[0.03280585,0.00182925,0.000009547983,0.0000698943,0.9637765,0.0001310536,0.0008217566,0.00007436646,0.0004818202],"genre_candidate":"editorial","genre_consensus":"editorial","teacher_disagreement_score":0.02212048,"threshold_uncertainty_score":0.9999024,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007019854513091919,"score_gpt":0.274580910297872,"score_spread":0.2675610557847801,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}