{"id":"W2761770213","doi":"10.1093/mmy/myx073","title":"The mitochondrial ABC transporter Atm1 plays a role in iron metabolism and virulence in the human fungal pathogen Cryptococcus neoformans","year":2017,"lang":"en","type":"article","venue":"Medical Mycology","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; Northeastern University; National Research Foundation of Korea; National Natural Science Foundation of China; Ministry of Science, ICT and Future Planning; National Research Foundation","keywords":"Cryptococcus neoformans; Biology; Virulence; Saccharomyces cerevisiae; Mutant; Mitochondrion; Biochemistry; ATP-binding cassette transporter; Microbiology; Fungal protein; Yeast; Cytosol; Transporter; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006924705,0.0001362472,0.0003339979,0.00005809135,0.0006971452,0.00003139618,0.0002682584,0.0002022136,0.0001433441],"category_scores_gemma":[0.0003883898,0.00006993421,0.0000621419,0.00006162051,0.0006517333,0.00006197287,0.00007079143,0.000601705,0.00001392125],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002345962,"about_ca_system_score_gemma":0.00006115257,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005028109,"about_ca_topic_score_gemma":0.00590171,"domain_scores_codex":[0.9986758,0.0001362156,0.0003220502,0.0002229879,0.0002658352,0.0003771721],"domain_scores_gemma":[0.9991758,0.0002863493,0.00007019508,0.0003476274,0.00002278555,0.00009721656],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001456999,0.001467364,0.8515757,0.0001657977,0.0002223001,0.002927905,0.0218272,0.000004596383,0.04301794,0.02324124,0.005378887,0.04871411],"study_design_scores_gemma":[0.002454339,0.0002914268,0.9587157,0.00004062097,0.0000545445,0.0001018096,0.0005147691,0.0000806461,0.00004181532,0.0009893128,0.03662941,0.00008560858],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9864888,0.0008672421,0.00001905804,0.007444709,0.0004735967,0.0005439813,0.000008381622,0.00001212713,0.004142106],"genre_scores_gemma":[0.9977362,0.0005421718,0.00003290089,0.0008344064,0.0004937245,0.0002493946,0.000004387692,0.000008160529,0.00009864443],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.10714,"threshold_uncertainty_score":0.5361948,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01281866245700045,"score_gpt":0.2936607739604692,"score_spread":0.2808421115034688,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}