{"id":"W2761770213","doi":"10.1093/mmy/myx073","title":"The mitochondrial ABC transporter Atm1 plays a role in iron metabolism and virulence in the human fungal pathogen Cryptococcus neoformans","year":2017,"lang":"en","type":"article","venue":"Medical Mycology","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; Northeastern University; National Research Foundation of Korea; National Natural Science Foundation of China; Ministry of Science, ICT and Future Planning; National Research Foundation","keywords":"Cryptococcus neoformans; Biology; Virulence; Saccharomyces cerevisiae; Mutant; Mitochondrion; Biochemistry; ATP-binding cassette transporter; Microbiology; Fungal protein; Yeast; Cytosol; Transporter; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009145545,0.0002363041,0.000141062,0.0002169073,0.0001988732,0.0002259871,0.000103387,0.0002174772,0.0009484921],"category_scores_gemma":[0.0000930812,0.00007368059,0.0001571502,0.0001416032,0.0001558936,0.0001403057,0.0001512358,0.0002336238,0.0001906075],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003320229,"about_ca_system_score_gemma":0.0002280066,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001518636,"about_ca_topic_score_gemma":0.0009497649,"domain_scores_codex":[0.9999512,0.000007108837,0.000004361625,0.000010238,0.00001422795,0.00001276181],"domain_scores_gemma":[0.9999527,0.000004635632,0.00001729965,0.000003100562,0.000007720783,0.00001459087],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002281888,0.00004778965,0.004339646,0.00006411951,0.00000652074,0.0003473454,0.0000299942,0.0001094089,0.9887668,0.0002256303,0.00008756897,0.005746858],"study_design_scores_gemma":[0.00004039479,0.000403724,0.1120825,0.00004419338,0.00007852213,0.004768637,0.000278907,0.00331692,0.8709673,0.0004134538,0.007586628,0.00001888467],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969918,0.001467421,0.0007128348,0.0001616068,0.000009246911,0.000006813116,0.0001220356,0.0000208913,0.0005072981],"genre_scores_gemma":[0.9980378,0.0005194589,0.0005514636,0.00002541853,0.000002869537,0.000003057938,0.0001139583,0.000002481299,0.000743549],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001518636,"threshold_uncertainty_score":0.003172994,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01281866245700045,"score_gpt":0.2936607739604692,"score_spread":0.2808421115034688,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}