{"id":"W2761972425","doi":"10.1097/pas.0000000000000958","title":"Targeted Genomic Profiling Reveals Recurrent KRAS Mutations in Mesonephric-like Adenocarcinomas of the Female Genital Tract","year":2017,"lang":"en","type":"article","venue":"The American Journal of Surgical Pathology","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":163,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"","keywords":"KRAS; Mesonephric duct; Genital tract; Biology; Adenocarcinoma; Cancer research; Medicine; Oncology; Mutation; Gene; Genetics; Cancer; Physiology; Kidney","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006303053,0.00009001992,0.0001636091,0.0004882775,0.0001172438,0.0001869616,0.00009753722,0.0001882382,0.0003830153],"category_scores_gemma":[0.0002317021,0.0001071749,0.0001289564,0.0002647871,0.000138787,0.00005872893,0.0001044902,0.0001018064,0.00008663255],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001631178,"about_ca_system_score_gemma":0.0001053451,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001203946,"about_ca_topic_score_gemma":0.001961721,"domain_scores_codex":[0.9999313,0.000008121288,0.000006347405,0.00001742482,0.00001995028,0.0000169096],"domain_scores_gemma":[0.9999161,0.00002099446,0.0000270068,0.000006866952,0.00001065574,0.00001841281],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004718991,0.00004201629,0.3352961,0.00005510574,0.00005689512,0.004814611,0.0001800598,0.0004103547,0.6491744,0.00009525976,0.00009625297,0.009307151],"study_design_scores_gemma":[0.00001466778,0.0003260807,0.9337869,0.000005675189,0.00005451151,0.0133131,0.0002040438,0.001167711,0.05040248,0.00007953534,0.0006383632,0.000006864373],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994715,0.0001565605,0.0001633695,0.00001077306,7.536516e-7,0.000002938789,0.00008060734,0.000005740802,0.0001078236],"genre_scores_gemma":[0.9993891,0.00009379565,0.0002937975,0.00001344424,9.800439e-7,0.000002398802,0.0001156847,0.00000149474,0.00008933406],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001203946,"threshold_uncertainty_score":0.002393901,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03001127723235915,"score_gpt":0.3109623122855384,"score_spread":0.2809510350531793,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}