{"id":"W2762583950","doi":"10.1097/mib.0000000000001270","title":"Enhanced TH17 Responses in Patients with IL10 Receptor Deficiency and Infantile-onset IBD","year":2017,"lang":"en","type":"article","venue":"Inflammatory Bowel Diseases","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto; McMaster Children's Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; Deutsche Forschungsgemeinschaft; Crohn's and Colitis Foundation; Leona M. and Harry B. Helmsley Charitable Trust; Israel Science Foundation; Crohn's and Colitis Foundation of America","keywords":"Flow cytometry; Peripheral blood mononuclear cell; Immunology; Interleukin 10; Immune system; T cell; Biology; Acquired immune system; Innate immune system; Medicine; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004005525,0.0008617665,0.0006120198,0.001362214,0.0005073226,0.0005168105,0.0002944803,0.0007452289,0.00301155],"category_scores_gemma":[0.001110995,0.000329337,0.0002831533,0.0005982795,0.0004602811,0.0003288623,0.0003081955,0.0006232074,0.0004270216],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002282447,"about_ca_system_score_gemma":0.0001771182,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003774162,"about_ca_topic_score_gemma":0.0004255745,"domain_scores_codex":[0.9997361,0.00006041822,0.00003671952,0.00007436311,0.00004335428,0.00004902115],"domain_scores_gemma":[0.9991973,0.0001952653,0.0003474514,0.00004920235,0.00005830956,0.0001524656],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002628499,0.0001953456,0.9334002,0.0001569188,0.00008267667,0.02167551,0.0005099446,0.0001260722,0.03297426,0.00008124273,0.0003348686,0.007834478],"study_design_scores_gemma":[0.00005653559,0.001029907,0.907694,0.00006180013,0.0001636127,0.0843109,0.0006072301,0.0004533356,0.004301896,0.0001046295,0.00119965,0.00001647061],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987566,0.0005117079,0.0001784797,0.00004365312,0.000008475806,0.000009445162,0.00008914236,0.00001792435,0.0003845087],"genre_scores_gemma":[0.9992186,0.0001883316,0.0002634607,0.00003353826,0.00002312323,0.000008329405,0.0001223705,0.00000595763,0.0001363025],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00301155,"threshold_uncertainty_score":0.01007468,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006166793899313072,"score_gpt":0.2164762377886028,"score_spread":0.2103094438892897,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}