{"id":"W2762679461","doi":"10.1021/acs.jpcc.7b06164","title":"Oligomerization Alters Binding Affinity between Amyloid Beta and a Modulator of Peptide Aggregation","year":2017,"lang":"en","type":"article","venue":"The Journal of Physical Chemistry C","topic":"Supramolecular Self-Assembly in Materials","field":"Materials Science","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Orionin Tutkimussäätiö; Tekes; Academy of Finland; National Institute on Aging; University of California","keywords":"Peptide; Amyloid (mycology); Chemistry; BETA (programming language); Biophysics; Cell biology; Biochemistry; Biology; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001392628,0.0001623327,0.0001318631,0.00009801488,0.00008620329,0.0001648278,0.0001267196,0.0002093534,0.001011079],"category_scores_gemma":[0.0002205786,0.00009777086,0.00008735776,0.000061925,0.0001561429,0.0001665756,0.000115548,0.0002288003,0.0001354638],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001285115,"about_ca_system_score_gemma":0.0000823512,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002463752,"about_ca_topic_score_gemma":0.0002513507,"domain_scores_codex":[0.999903,0.00002373619,0.000005415226,0.0000258558,0.00001865519,0.00002340035],"domain_scores_gemma":[0.9999144,0.0000376787,0.00002022564,0.000005982202,0.000007465746,0.0000141198],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003906754,0.00002165141,0.0001387012,0.000009887548,0.000002063451,0.00001196914,0.00001296494,0.00005487205,0.9992244,0.00004272266,0.00001146619,0.0004301913],"study_design_scores_gemma":[0.000009304397,0.000332121,0.00459832,0.000003893656,0.000008927963,0.000116029,0.00002725986,0.0018214,0.9922469,0.00005300447,0.0007775301,0.000005284344],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987251,0.0002662157,0.0005785939,0.00001387081,0.000003154053,0.000004894942,0.00001431142,0.00001273251,0.0003811531],"genre_scores_gemma":[0.9989203,0.0001503302,0.0005928362,0.00002328022,0.000001650118,0.000006358524,0.00002564823,0.000004212454,0.000275288],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001011079,"threshold_uncertainty_score":0.003382385,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01742102272369718,"score_gpt":0.2729716939199033,"score_spread":0.2555506711962062,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}