{"id":"W2762701444","doi":"10.1093/annonc/mdx370.055","title":"ARASENS: A phase 3 trial of darolutamide in males with metastatic hormone-sensitive prostate cancer (mHSPC)","year":2017,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Medicine; Docetaxel; Androgen deprivation therapy; Prostate cancer; Internal medicine; Oncology; Placebo; Androgen receptor; Randomization; Randomized controlled trial; Chemotherapy; Cancer; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008103955,0.001199527,0.001341055,0.0004971678,0.0003968118,0.0008896472,0.0008535124,0.00113964,0.008544904],"category_scores_gemma":[0.0007823327,0.0003927151,0.001652212,0.0003594497,0.0008158579,0.0007371433,0.000418478,0.00360941,0.001565088],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007046427,"about_ca_system_score_gemma":0.001276219,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001638281,"about_ca_topic_score_gemma":0.006834803,"domain_scores_codex":[0.9997656,0.0001026568,0.000007309778,0.00003829414,0.00002414942,0.00006203749],"domain_scores_gemma":[0.9996331,0.00006175215,0.00005146395,0.00002521603,0.00002128211,0.0002071074],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6207575,0.03527283,0.005791448,0.001943663,0.003155674,0.0003952753,0.0004947555,0.005320807,0.03805691,0.001555423,0.01970119,0.2675545],"study_design_scores_gemma":[0.7989248,0.1761891,0.008895445,0.00009559377,0.0006362173,0.0005553373,0.0001343309,0.001653235,0.002553702,0.0007674026,0.009541167,0.00005381269],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.977877,0.006379766,0.0009057127,0.002111715,0.0005019544,0.002214128,0.003057266,0.0005667681,0.006385719],"genre_scores_gemma":[0.9742494,0.005111972,0.002684974,0.00198821,0.0002197746,0.001706057,0.004735351,0.0001129882,0.00919146],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008544904,"threshold_uncertainty_score":0.02858549,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.166572910446867,"score_gpt":0.4890637230435366,"score_spread":0.3224908125966696,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}