{"id":"W2762704796","doi":"10.1093/eep/dvx015","title":"Maintenance of Mest imprinted methylation in blastocyst-stage mouse embryos is less stable than other imprinted loci following superovulation or embryo culture","year":2017,"lang":"en","type":"review","venue":"Current Zoology","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children’s Health Research Institute; Western University","funders":"","keywords":"Genomic imprinting; Methylation; Blastocyst; Biology; Imprinting (psychology); DNA methylation; Andrology; Embryo; Insulin-like growth factor 2 receptor; Epigenetics; Embryo culture; Genetics; Embryogenesis; Gene; Growth factor; Gene expression; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005004317,0.0005342906,0.0008041338,0.001192432,0.0001485296,0.0006296131,0.0007914964,0.0006159789,0.002479853],"category_scores_gemma":[0.0004783485,0.0001859335,0.0002204543,0.001157284,0.0003960236,0.0007710107,0.0004491583,0.001084796,0.001932404],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004008812,"about_ca_system_score_gemma":0.0006289156,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005287727,"about_ca_topic_score_gemma":0.001287,"domain_scores_codex":[0.9998922,0.00001285982,0.00001794096,0.00002083997,0.00004560353,0.00001043643],"domain_scores_gemma":[0.9997676,0.0001010178,0.00004311201,0.000009535731,0.00005375199,0.00002495543],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0000682001,0.00001822125,0.000196743,0.01033317,0.00005639479,0.000157672,0.00002561419,0.0001870324,0.004856507,0.003106357,0.01990047,0.9610937],"study_design_scores_gemma":[0.000008509353,0.00004425746,0.0008575664,0.001092414,0.0000705713,0.00101255,0.0000262868,0.00003935154,0.002040119,0.001168906,0.9936255,0.00001395234],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001845367,0.9978859,0.0002077655,0.0002470773,0.0002050921,0.000002947898,0.00003610382,0.00001190194,0.001218708],"genre_scores_gemma":[0.0009134322,0.9976873,0.0001908855,0.0001457636,0.0001134777,0.000004771151,0.00005367561,0.000002975304,0.000887622],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002479853,"threshold_uncertainty_score":0.008295953,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08081879887219379,"score_gpt":0.3688625839421011,"score_spread":0.2880437850699074,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}