{"id":"W2762830460","doi":"10.1093/annonc/mdx371.006","title":"Subgroup analyses from KEYNOTE-045: Pembrolizumab (pembro) versus individual investigator’s choice of chemotherapy (paclitaxel, docetaxel, or vinflunine) in recurrent, advanced urothelial cancer (uc)","year":2017,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"","keywords":"Docetaxel; Medicine; Paclitaxel; Internal medicine; Oncology; Pembrolizumab; Chemotherapy; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008327225,0.002592393,0.007534416,0.001004388,0.00044681,0.002047838,0.001697304,0.002389808,0.0069385],"category_scores_gemma":[0.01520778,0.001013845,0.02381821,0.001102358,0.0006114094,0.002213817,0.00153237,0.005231707,0.0005575101],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001403297,"about_ca_system_score_gemma":0.00157677,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003506465,"about_ca_topic_score_gemma":0.009329415,"domain_scores_codex":[0.9920728,0.004483296,0.001026604,0.001139263,0.0004636546,0.000814478],"domain_scores_gemma":[0.9950495,0.002938002,0.0007393116,0.0007117828,0.0002120906,0.0003492543],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.767343,0.0004243989,0.009918655,0.007217024,0.1804992,0.0003421429,0.0002341727,0.003172679,0.002216182,0.000520282,0.006962562,0.02114971],"study_design_scores_gemma":[0.4218894,0.04063542,0.07237328,0.001669233,0.4269622,0.0006133177,0.0009624424,0.01105708,0.003062033,0.006462377,0.01377473,0.0005384749],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8767081,0.08428836,0.005577706,0.002827063,0.00551656,0.002401873,0.01506645,0.0004168143,0.007197002],"genre_scores_gemma":[0.9846596,0.003660619,0.001684806,0.001460053,0.0008615032,0.001243765,0.003004818,0.00009896697,0.003325992],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008327225,"threshold_uncertainty_score":0.04403913,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3080008068206369,"score_gpt":0.5058922580437564,"score_spread":0.1978914512231195,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}