{"id":"W2762965851","doi":"10.1089/scd.2017.0090","title":"Optimizing Human Induced Pluripotent Stem Cell Expansion in Stirred-Suspension Culture","year":2017,"lang":"en","type":"article","venue":"Stem Cells and Development","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Induced pluripotent stem cell; Biology; Bioreactor; Embryonic stem cell; Human Induced Pluripotent Stem Cells; Regenerative medicine; Germ layer; Suspension culture; Seeding; Chemically defined medium; Suspension (topology); Cell culture; Cell biology; Biotechnology; Stem cell; Botany; In vitro; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001595863,0.0008498151,0.0005741721,0.0005689106,0.0004070652,0.000734394,0.000563392,0.0004950414,0.0008157639],"category_scores_gemma":[0.001148427,0.0002147503,0.0004206474,0.0006614525,0.0003064443,0.0005438933,0.000499736,0.0005881921,0.0007219315],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004723512,"about_ca_system_score_gemma":0.0006733288,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001194194,"about_ca_topic_score_gemma":0.002800282,"domain_scores_codex":[0.9989221,0.000210193,0.0001695316,0.0001972531,0.0004239481,0.00007698889],"domain_scores_gemma":[0.9995655,0.0001625258,0.00008563037,0.00003360151,0.0001245603,0.0000281577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005655268,0.00007212141,0.0004991949,0.0001241302,0.000007852006,0.00007912674,0.00005341672,0.001016724,0.9931896,0.0001223012,0.00009771855,0.00468122],"study_design_scores_gemma":[0.00001432733,0.0001845512,0.001735876,0.00001316141,0.00003341458,0.00007868525,0.00002926973,0.002532413,0.9929218,0.00004951404,0.002389899,0.00001714482],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7590457,0.006231699,0.2241716,0.0003693977,0.0002235144,0.001311034,0.001175008,0.0009660173,0.006506029],"genre_scores_gemma":[0.7758542,0.005223107,0.2120171,0.0001692368,0.00008563901,0.001036351,0.002567111,0.000232844,0.002814385],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001595863,"threshold_uncertainty_score":0.008439839,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0312588455918848,"score_gpt":0.2739688865430893,"score_spread":0.2427100409512045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}