{"id":"W2763148117","doi":"10.1016/j.exer.2017.10.005","title":"Growth hormone protects against kainate excitotoxicity and induces BDNF and NT3 expression in chicken neuroretinal cells","year":2017,"lang":"en","type":"article","venue":"Experimental Eye Research","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Consejo Nacional de Ciencia y Tecnología","keywords":"Excitotoxicity; Neuroprotection; Kainate receptor; Inner plexiform layer; Neurotrophin; Neurotrophic factors; Kainic acid; Inner nuclear layer; Ganglion cell layer; Retina; Cell biology; Biology; Brain-derived neurotrophic factor; Endocrinology; Internal medicine; Neuroscience; Glutamate receptor; Programmed cell death; Apoptosis; Medicine; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001075687,0.0003105821,0.0002546706,0.0003614248,0.0002577546,0.0003268668,0.0002231168,0.0002517301,0.001389093],"category_scores_gemma":[0.0001577416,0.0001913357,0.0002528896,0.0001337586,0.0004953128,0.0002731596,0.0002011508,0.0006735133,0.0003500872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005331656,"about_ca_system_score_gemma":0.0003844485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004655163,"about_ca_topic_score_gemma":0.008541802,"domain_scores_codex":[0.9998878,0.00001388576,0.00001357805,0.00002705051,0.00002068174,0.00003683921],"domain_scores_gemma":[0.9997838,0.00005183728,0.00003924255,0.0000399909,0.00002421461,0.00006099653],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002489094,0.000008931846,0.0001097559,0.00001308061,0.000002866469,0.00004899911,0.0000251995,0.00001372899,0.9991769,0.00004098126,0.00001633981,0.0002942769],"study_design_scores_gemma":[0.00003138506,0.0001871161,0.005251146,0.000005681265,0.00001610113,0.0001076449,0.0001093467,0.0001805434,0.992449,0.00003678051,0.001619978,0.00000531495],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960428,0.001293326,0.0007513363,0.0001620435,0.00004277191,0.00001206853,0.0002804998,0.00005208566,0.001363061],"genre_scores_gemma":[0.9916781,0.0006359495,0.0008418345,0.00008381299,0.00001518384,0.00001936491,0.0004396226,0.00005063088,0.006235522],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004655163,"threshold_uncertainty_score":0.009256124,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02818151256572525,"score_gpt":0.3499004737663926,"score_spread":0.3217189612006673,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}