{"id":"W2763148117","doi":"10.1016/j.exer.2017.10.005","title":"Growth hormone protects against kainate excitotoxicity and induces BDNF and NT3 expression in chicken neuroretinal cells","year":2017,"lang":"en","type":"article","venue":"Experimental Eye Research","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Consejo Nacional de Ciencia y Tecnología","keywords":"Excitotoxicity; Neuroprotection; Kainate receptor; Inner plexiform layer; Neurotrophin; Neurotrophic factors; Kainic acid; Inner nuclear layer; Ganglion cell layer; Retina; Cell biology; Biology; Brain-derived neurotrophic factor; Endocrinology; Internal medicine; Neuroscience; Glutamate receptor; Programmed cell death; Apoptosis; Medicine; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005772895,0.0001741622,0.0001553641,0.00008162449,0.0005314114,0.0002037187,0.0003651561,0.0001851403,0.000005357418],"category_scores_gemma":[0.0001866816,0.0001555444,0.0000270196,0.00005413503,0.0006321198,0.00002464843,0.0008775316,0.0003697916,0.000003314238],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002772655,"about_ca_system_score_gemma":0.00006878359,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006378177,"about_ca_topic_score_gemma":0.000002967844,"domain_scores_codex":[0.9983335,0.0002036699,0.000163691,0.0005595096,0.000322968,0.0004166982],"domain_scores_gemma":[0.9993183,0.00001758447,0.00007016451,0.0003777663,0.00006681494,0.0001493649],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001811815,0.00009541275,0.001898365,0.00005063841,0.000005199943,0.00003710941,0.0002493508,3.230765e-7,0.9967586,0.00002185961,0.0001294082,0.000572513],"study_design_scores_gemma":[0.0008305368,0.0004792831,0.00801955,0.00005432789,6.290959e-7,0.000006614376,0.0004310336,0.00003221959,0.9895148,0.00008868259,0.0003666181,0.000175677],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922199,0.004130789,0.000009440367,0.00008896305,0.00004191661,0.0004395159,0.000003952218,0.000007397058,0.003058111],"genre_scores_gemma":[0.9977764,0.001410928,0.0002107915,0.00002731228,0.0001453744,0.0001190349,0.00001144069,0.00002480391,0.000273932],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007243811,"threshold_uncertainty_score":0.6342918,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02818151256572525,"score_gpt":0.3499004737663926,"score_spread":0.3217189612006673,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}