{"id":"W2763238997","doi":"10.1111/imr.12582","title":"Immunogenic stress and death of cancer cells: Contribution of antigenicity vs adjuvanticity to immunosurveillance","year":2017,"lang":"en","type":"review","venue":"Immunological Reviews","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":100,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Maisonneuve-Rosemont; Université de Montréal; Institute for Research in Immunology and Cancer","funders":"European Research Council; Institut National Du Cancer; Institut Universitaire de France; Ligue Contre le Cancer; Fondation pour la Recherche Médicale; Agence Nationale de la Recherche; Association pour la Recherche sur le Cancer","keywords":"Immunosurveillance; Biology; Autophagy; Immune system; Immunogenic cell death; Calreticulin; Antigenicity; Cancer cell; Immunology; Antigen; Cell biology; Major histocompatibility complex; Cancer immunotherapy; MHC class I; Innate immune system; Cancer research; Cancer; Immunotherapy; Endoplasmic reticulum; Apoptosis; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001664676,0.0002043385,0.000163868,0.0001439988,0.00005782587,0.0002000755,0.00007900797,0.000189797,0.0008142092],"category_scores_gemma":[0.0001076071,0.00006267278,0.000116604,0.0000619579,0.0001748717,0.0001818355,0.0001571907,0.0002679348,0.00008607851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000163859,"about_ca_system_score_gemma":0.00005905995,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006865568,"about_ca_topic_score_gemma":0.00005994964,"domain_scores_codex":[0.9999434,0.00001331401,0.000005119515,0.00001116443,0.00001290515,0.00001418654],"domain_scores_gemma":[0.999871,0.00004437281,0.00003575855,0.000007502844,0.00001191073,0.00002945061],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000132154,0.00001083522,0.0008424359,0.0000369291,0.00000399005,0.00003305625,0.000007802259,0.00007950945,0.9977545,0.00006756979,0.000008832691,0.001022246],"study_design_scores_gemma":[0.00001720855,0.0007108897,0.02903941,0.00001161155,0.00003431761,0.0006546266,0.00005532123,0.003397592,0.9647516,0.0002951174,0.00102457,0.00000771627],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9966415,0.00182529,0.001012835,0.00004076761,0.000009892575,0.000009335915,0.00004607454,0.000006977476,0.0004072335],"genre_scores_gemma":[0.9990047,0.0003584254,0.0003500255,0.00002974561,0.000008063422,0.000005617838,0.00003637341,0.000001844936,0.0002051887],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.0008142092,"threshold_uncertainty_score":0.002723753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09352814634102885,"score_gpt":0.3914029269305527,"score_spread":0.2978747805895238,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}