{"id":"W2763427638","doi":"10.1021/acs.jmedchem.7b01209","title":"Influences of Histidine-1 and Azaphenylalanine-4 on the Affinity, Anti-inflammatory, and Antiangiogenic Activities of Azapeptide Cluster of Differentiation 36 Receptor Modulators","year":2017,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Chemistry; CD36; Receptor; Peptide; Histidine; Nitric oxide; Angiogenesis; Biochemistry; Amino acid; Stereochemistry; Cancer research","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003109257,0.0001686319,0.0004351003,0.00002904523,0.0001264386,0.00001889009,0.0003747501,0.000136926,0.0001905644],"category_scores_gemma":[0.0004599544,0.0001199338,0.0001272216,0.00003781326,0.0006072825,0.0001066862,0.0001004782,0.0002791564,1.503979e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002157408,"about_ca_system_score_gemma":0.00006956091,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001150165,"about_ca_topic_score_gemma":8.280733e-7,"domain_scores_codex":[0.9986603,0.00001391524,0.0006525217,0.0001426558,0.0004077966,0.0001227625],"domain_scores_gemma":[0.9971348,0.0003118291,0.001907112,0.0003884578,0.0001637321,0.00009403586],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001452925,0.00008052166,0.04973112,0.0008109769,0.0001305526,0.000001664499,0.0002335021,0.000007505692,0.9481763,0.00002490856,0.0002253499,0.0004322744],"study_design_scores_gemma":[0.0006946446,0.00003464831,0.03547976,0.0007605006,0.0001398156,0.00005209471,0.0005694146,0.00005085583,0.9618754,0.0001382866,0.0001081442,0.00009640624],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981574,0.0002785494,0.000006891318,0.0005712796,0.00003337048,0.00003695039,0.00003856129,0.000003931635,0.0008730022],"genre_scores_gemma":[0.9992069,0.0003525157,0.00005283762,0.00001007319,0.0002416106,0.000002386853,0.000004688548,0.00001099709,0.000117962],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01425136,"threshold_uncertainty_score":0.4890758,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01469973680693728,"score_gpt":0.2510254799541778,"score_spread":0.2363257431472405,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}