{"id":"W2763570236","doi":"10.1039/c7re00125h","title":"Telescoped continuous flow generation of a library of highly substituted 3-thio-1,2,4-triazoles","year":2017,"lang":"en","type":"article","venue":"Reaction Chemistry & Engineering","topic":"Innovative Microfluidic and Catalytic Techniques Innovation","field":"Engineering","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Krembil Foundation; Toronto Public Health","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Thio-; Continuous flow; Residence time (fluid dynamics); Chemistry; Combinatorial chemistry; Computer science; Stereochemistry; Engineering; Biochemical engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009882398,0.0001592445,0.000239762,0.00007286196,0.00004755706,0.00002826485,0.0001882352,0.0001449336,0.00002335237],"category_scores_gemma":[0.00007170685,0.0001810131,0.00005306705,0.0001536646,0.00004380783,0.0003906507,0.00003220571,0.0001694328,0.000001561787],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005109136,"about_ca_system_score_gemma":0.00002733552,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006437301,"about_ca_topic_score_gemma":4.015549e-8,"domain_scores_codex":[0.9991989,0.000002333743,0.0004042776,0.0001333302,0.0001251657,0.0001359903],"domain_scores_gemma":[0.9992908,0.00001349098,0.0001769312,0.0003881713,0.0001050231,0.00002557046],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000006752191,0.00001380331,0.00007119554,0.0002264751,0.00004340012,0.000001808499,0.00002946011,0.001279652,0.994169,0.0003689976,0.0005413953,0.003248064],"study_design_scores_gemma":[0.0002373568,0.000005394214,0.0005266158,0.0001060532,0.00001479723,0.000009317296,0.00001104447,0.02276197,0.9723459,0.000007431279,0.003823071,0.0001510395],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8692188,0.0001996487,0.1266931,0.00002122946,0.0002898167,0.0001241981,0.00003608305,0.000426793,0.0029904],"genre_scores_gemma":[0.9955866,0.00005650824,0.003811715,0.000002077725,0.0002269095,0.00001471754,0.0001708053,0.00003758714,0.00009307141],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1263679,"threshold_uncertainty_score":0.7381501,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01456501303287919,"score_gpt":0.2163570382745543,"score_spread":0.2017920252416751,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}