{"id":"W2763900685","doi":"10.1074/jbc.m117.812842","title":"PelA and PelB proteins form a modification and secretion complex essential for Pel polysaccharide-dependent biofilm formation in Pseudomonas aeruginosa","year":2017,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; University of Calgary; Hospital for Sick Children; University of Toronto","funders":"National Institutes of Health; Canada Excellence Research Chairs, Government of Canada; Canada Research Chairs; Canadian Institutes of Health Research; Sick Kids Foundation; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Cystic Fibrosis Canada","keywords":"Periplasmic space; Tetratricopeptide; Biofilm; Chemistry; Porin; Bacterial outer membrane; Microbiology; Biochemistry; Biology; Bacteria; Gene; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001973434,0.0004282078,0.0003285332,0.000301505,0.0004717649,0.0004297544,0.0002169142,0.000475539,0.00112078],"category_scores_gemma":[0.0003383575,0.0002922091,0.0003447155,0.0002304268,0.0002421555,0.0003599344,0.0005973172,0.000609929,0.0009588036],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007335109,"about_ca_system_score_gemma":0.0004473082,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002797703,"about_ca_topic_score_gemma":0.002882972,"domain_scores_codex":[0.9996912,0.00003805575,0.00002036486,0.0000632335,0.0001454491,0.00004175981],"domain_scores_gemma":[0.9998639,0.00001333635,0.00003617966,0.00001665546,0.00002091065,0.00004906315],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004079207,0.00002525396,0.0006585054,0.00001788711,0.000004903231,0.0001008294,0.00002466263,0.00003777268,0.9979531,0.00007641914,0.00005126563,0.001008574],"study_design_scores_gemma":[0.00003105238,0.0001803914,0.05283675,0.00001322546,0.00002432555,0.001325368,0.0001620356,0.004126965,0.93354,0.000214205,0.007522122,0.00002343076],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915867,0.001490608,0.004759908,0.0003046046,0.00003532422,0.00004341578,0.0003951299,0.0001008144,0.001283498],"genre_scores_gemma":[0.9889797,0.0004747554,0.005059354,0.0001075864,0.00001157967,0.00004572792,0.001407264,0.00003676873,0.003877303],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002797703,"threshold_uncertainty_score":0.005562901,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03297510488336664,"score_gpt":0.2798434527729721,"score_spread":0.2468683478896054,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}