{"id":"W2763900685","doi":"10.1074/jbc.m117.812842","title":"PelA and PelB proteins form a modification and secretion complex essential for Pel polysaccharide-dependent biofilm formation in Pseudomonas aeruginosa","year":2017,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; University of Calgary; Hospital for Sick Children; University of Toronto","funders":"National Institutes of Health; Canada Excellence Research Chairs, Government of Canada; Canada Research Chairs; Canadian Institutes of Health Research; Sick Kids Foundation; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Cystic Fibrosis Canada","keywords":"Periplasmic space; Tetratricopeptide; Biofilm; Chemistry; Porin; Bacterial outer membrane; Microbiology; Biochemistry; Biology; Bacteria; Gene; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002968865,0.0001317465,0.000200464,0.00002294804,0.0001612007,0.0001041573,0.0001303067,0.0002527188,0.000005799548],"category_scores_gemma":[0.000195215,0.0001024766,0.00007128827,0.00001470496,0.0001249311,0.0000277625,0.00009071992,0.0001165794,2.14024e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000191345,"about_ca_system_score_gemma":0.00002447482,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000128704,"about_ca_topic_score_gemma":0.000007626927,"domain_scores_codex":[0.9991784,0.00002041765,0.0003544375,0.0001941377,0.00008127445,0.0001713268],"domain_scores_gemma":[0.99915,0.00001290934,0.0004964459,0.0001540607,0.0001089562,0.00007766661],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003938767,0.00004180981,0.000903799,0.00005056446,0.00001312772,0.000003460726,0.00002795028,8.240465e-7,0.9961243,0.00001991492,0.0000276456,0.002392716],"study_design_scores_gemma":[0.001246382,0.0002615201,0.01556422,0.0000389777,0.00001580434,0.0003082457,0.0001070868,0.0003277406,0.9814488,0.00017333,0.0003581969,0.0001496958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978462,0.0001703302,0.001097875,0.0005360605,0.00005597546,0.0001936894,0.0000291511,0.000003238981,0.00006748697],"genre_scores_gemma":[0.9975824,0.0003813594,0.001571781,0.00003496872,0.0003329022,0.000006129679,0.0000620124,0.000006650268,0.00002182746],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01467551,"threshold_uncertainty_score":0.4178873,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03297510488336664,"score_gpt":0.2798434527729721,"score_spread":0.2468683478896054,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}