{"id":"W2763930264","doi":"10.1200/jco.2017.35.15_suppl.tps4131","title":"CheckMate 577: A randomized, double-blind, phase 3 study of adjuvant nivolumab (nivo) or placebo in pts with resected esophageal (E) or gastroesophageal junction (GEJ) cancer.","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Esophageal Cancer Research and Treatment","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Medicine; Internal medicine; Cancer; Nivolumab; Placebo; Gastroesophageal Junction; Oncology; Adjuvant; Randomization; Chemotherapy; Esophageal cancer; Gastroenterology; Surgery; Clinical trial; Adenocarcinoma; Immunotherapy; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001266031,0.001304728,0.002106904,0.0004479839,0.0003748714,0.001132448,0.0009165294,0.001565735,0.007942448],"category_scores_gemma":[0.001244788,0.0006473292,0.001448843,0.0003289259,0.00084219,0.0008359051,0.0003656099,0.002744411,0.001296538],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000781712,"about_ca_system_score_gemma":0.001414311,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001237583,"about_ca_topic_score_gemma":0.003358364,"domain_scores_codex":[0.9997179,0.0001375603,0.00001335632,0.00005219295,0.00002317212,0.00005582599],"domain_scores_gemma":[0.9994655,0.0001436127,0.0001115073,0.00003613477,0.00003784848,0.0002053709],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9660361,0.01094405,0.0005478308,0.0007533741,0.0007261373,0.0000374728,0.0000461592,0.0003828017,0.004142639,0.0001496274,0.001712505,0.01452125],"study_design_scores_gemma":[0.9529065,0.04443875,0.0008590405,0.00002690471,0.0002935668,0.0000189288,0.00001340334,0.0004493602,0.0003303368,0.0000957671,0.0005565595,0.00001088616],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9797142,0.004421996,0.001080003,0.0008832824,0.0009581345,0.006788508,0.002122273,0.0003321384,0.00369936],"genre_scores_gemma":[0.9780343,0.00290744,0.001941705,0.002410838,0.000396585,0.007256269,0.002068544,0.00005749632,0.004926826],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007942448,"threshold_uncertainty_score":0.02657008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2158395190838099,"score_gpt":0.538471722240513,"score_spread":0.3226322031567031,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}