{"id":"W2764062536","doi":"10.1371/journal.pone.0185653","title":"Egg white hydrolysate shows insulin mimetic and sensitizing effects in 3T3-F442A pre-adipocytes","year":2017,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Protein Hydrolysis and Bioactive Peptides","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Alberta Livestock and Meat Agency; Egg Farmers of Canada","keywords":"Insulin resistance; Internal medicine; Endocrinology; Metabolic syndrome; Insulin receptor; Adipose tissue; Adiponectin; Downregulation and upregulation; Protein kinase B; Insulin; Oxidative stress; Adipocyte; Chemistry; Phosphorylation; Biology; Medicine; Diabetes mellitus; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002606464,0.000203547,0.0003050661,0.00006182553,0.0001591555,0.0001116975,0.0002093164,0.0001644718,0.000006955445],"category_scores_gemma":[0.0003341543,0.0001902623,0.00006032363,0.0000367575,0.0001486477,0.00001378823,0.0002772373,0.0001476023,0.00000965915],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001454712,"about_ca_system_score_gemma":0.00002101891,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008238919,"about_ca_topic_score_gemma":0.0001864874,"domain_scores_codex":[0.9987933,0.00009062143,0.0001916795,0.0004653183,0.0001570426,0.0003020141],"domain_scores_gemma":[0.9990889,0.00002555656,0.0001418499,0.0005973015,0.00004875773,0.00009756385],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001101469,0.0002738284,0.0582258,0.0001052869,0.0001810119,0.00001994783,0.00007498252,0.000004340762,0.9384559,0.000007910389,0.000008859689,0.002532026],"study_design_scores_gemma":[0.0007685237,0.0002648337,0.08815739,0.0001929542,0.00008737859,0.000005370974,0.000008358037,0.0009470711,0.9090762,0.000147795,0.00009522837,0.0002488754],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964529,0.002211876,0.00003533359,0.0002400456,0.00002555172,0.0003815289,0.000008967476,0.00001437408,0.0006293778],"genre_scores_gemma":[0.9972008,0.0004091473,0.001574168,0.000153357,0.0001659245,0.00004983418,0.00001895143,0.00002624778,0.0004015379],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02993159,"threshold_uncertainty_score":0.7758673,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01708266954031556,"score_gpt":0.2287657106077612,"score_spread":0.2116830410674456,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}