{"id":"W2764151966","doi":"10.1016/j.trecan.2017.09.004","title":"Lysophosphatidate Signaling: The Tumor Microenvironment’s New Nemesis","year":2017,"lang":"en","type":"review","venue":"Trends in cancer","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":false,"ca_institutions":"Memorial University of Newfoundland; University of Alberta","funders":"","keywords":"Tumor microenvironment; Mediator; Inflammation; Cancer; Cancer research; Fibrosis; Signal transduction; Biology; Medicine; Bioinformatics; Tumor cells; Immunology; Internal medicine; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007096484,0.0007773904,0.001051571,0.001060476,0.0002618124,0.001582496,0.0009286485,0.001535825,0.003471283],"category_scores_gemma":[0.0007000043,0.0001836563,0.0002988714,0.001213358,0.0007640026,0.00214779,0.001120006,0.002684569,0.0018228],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007569693,"about_ca_system_score_gemma":0.001319823,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006126311,"about_ca_topic_score_gemma":0.001438811,"domain_scores_codex":[0.9998332,0.0000236237,0.00001713166,0.00002803955,0.00007138618,0.00002652811],"domain_scores_gemma":[0.9997548,0.00008165753,0.00002860561,0.000009414032,0.00007768578,0.00004781994],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001424652,0.00004575073,0.0002208976,0.00623678,0.0000650579,0.0003554837,0.00007326833,0.0002790709,0.004095197,0.01201036,0.06642269,0.9100531],"study_design_scores_gemma":[0.00001275377,0.00003661526,0.0002547898,0.0007869364,0.00003722799,0.0005535285,0.00005099443,0.00007102618,0.0004746001,0.003021381,0.9946895,0.00001066087],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001443803,0.9962544,0.0002379837,0.001428254,0.0009116203,0.000002849079,0.00002105419,0.00001229598,0.0009870747],"genre_scores_gemma":[0.001185547,0.9959838,0.0001866633,0.0007278365,0.0007974753,0.000004306066,0.00003148032,0.000002161803,0.001080745],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003471283,"threshold_uncertainty_score":0.01161259,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1066791627737327,"score_gpt":0.3907619221125657,"score_spread":0.284082759338833,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}