{"id":"W2764173292","doi":"10.1016/j.bone.2017.09.021","title":"Effects of single or combination therapy of teriparatide and anti-RANKL monoclonal antibody on bone defect regeneration in mice","year":2017,"lang":"en","type":"article","venue":"Bone","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Bayer Canada","keywords":"Cancellous bone; Cortical bone; Bone healing; RANKL; Teriparatide; Chemistry; Medullary cavity; Bone mineral; Medicine; Endocrinology; Osteoporosis; Internal medicine; Anatomy; Receptor; Activator (genetics)","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009344845,0.00008352328,0.0001732134,0.0000388139,0.00004554069,0.0000154003,0.00005487792,0.00006218837,0.000001957806],"category_scores_gemma":[0.0001143943,0.00006927982,0.00004105907,0.00002361421,0.00007099738,0.000008020805,0.00002835633,0.00002141156,4.547656e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000224438,"about_ca_system_score_gemma":0.00002476772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000602016,"about_ca_topic_score_gemma":0.00003095323,"domain_scores_codex":[0.9994888,0.00004944722,0.0001520897,0.000156888,0.00007445621,0.00007827238],"domain_scores_gemma":[0.9995791,0.00001710003,0.0001533459,0.0001876834,0.0000375824,0.00002521499],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004604592,0.0003900334,0.00655685,0.00004963397,0.00001422373,0.000004061828,0.00002051486,0.000005980436,0.9897913,0.0001269758,0.00006462075,0.002515294],"study_design_scores_gemma":[0.001611626,0.000332519,0.2522552,0.00003025571,0.00000933888,0.000002134315,0.000002721877,0.00001991849,0.7454711,0.00004428963,0.0001609406,0.00005994799],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959975,0.003490104,0.00009051492,0.00004644283,0.00005670721,0.0001835796,0.00001259563,0.000002099091,0.0001204944],"genre_scores_gemma":[0.9985541,0.001029395,0.0001769834,0.0000386445,0.00003859738,0.000007571098,0.00005403955,0.000007759169,0.00009292894],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2456983,"threshold_uncertainty_score":0.2825149,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01336613531591685,"score_gpt":0.276063993815429,"score_spread":0.2626978584995121,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}