{"id":"W2764216010","doi":"10.1371/journal.pone.0185177","title":"Rapid enteric testing to permit targeted antimicrobial therapy, with and without Lactobacillus reuteri probiotics, for paediatric acute diarrhoeal disease in Botswana: A pilot, randomized, factorial, controlled trial","year":2017,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Probiotics and Fermented Foods","field":"Agricultural and Biological Sciences","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Impact; McMaster University","funders":"Government of Canada; Grand Challenges Canada; Center for AIDS Research, University of Washington; Hamilton Health Sciences; Hamilton Health Sciences Foundation; University of Pennsylvania","keywords":"Medicine; Placebo; Internal medicine; Diarrhea; Lactobacillus reuteri; Randomized controlled trial; Probiotic; Clinical endpoint; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005882547,0.001946521,0.003060079,0.0006373312,0.0005283741,0.000940037,0.001252812,0.001951343,0.004776156],"category_scores_gemma":[0.004315555,0.0009317261,0.002645011,0.0007330407,0.001986852,0.0009914133,0.0008030893,0.001773945,0.0005609248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009644723,"about_ca_system_score_gemma":0.002234906,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001322094,"about_ca_topic_score_gemma":0.00181777,"domain_scores_codex":[0.9971128,0.001821178,0.0002616525,0.0002886548,0.0001697023,0.0003460383],"domain_scores_gemma":[0.9963744,0.001384385,0.0009652076,0.0003025582,0.0003053855,0.0006680323],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9746114,0.01478737,0.0007019363,0.0006085369,0.0004716887,0.00003992556,0.00007612375,0.0001464567,0.002169345,0.00005804438,0.0001140926,0.006215055],"study_design_scores_gemma":[0.7373685,0.2603104,0.001313615,0.00003450815,0.0003318756,0.00001611134,0.00002308654,0.0001300183,0.0002837575,0.0000330088,0.0001469462,0.000008114375],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9854288,0.00178959,0.0007579503,0.0002795208,0.0003453383,0.01053386,0.0003481448,0.00005163106,0.0004651425],"genre_scores_gemma":[0.9730058,0.001697364,0.00417984,0.0005216293,0.0003582293,0.01870571,0.0003394184,0.00001375648,0.001178201],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005882547,"threshold_uncertainty_score":0.03111023,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05369546958832455,"score_gpt":0.2382068354377864,"score_spread":0.1845113658494618,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}