{"id":"W2764252694","doi":"10.2174/1567205014666171004113537","title":"Reduced Serotonin Transporter Levels and Inflammation in the Midbrain Raphe of 12 Month Old APP<sub>swe</sub>/PSEN<sub>1dE9</sub> Mice","year":2018,"lang":"en","type":"article","venue":"Current Alzheimer Research","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Serotonin transporter; Raphe; Serotonin; Midbrain; Raphe nuclei; Inflammation; Neuroscience; Internal medicine; Psychology; Medicine; Biology; Serotonergic; Central nervous system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002694102,0.0004167011,0.0005863166,0.0007855585,0.0003168749,0.0000915128,0.0004522567,0.0002013638,0.00009270015],"category_scores_gemma":[0.0002133512,0.0003041129,0.0002079396,0.001174111,0.001118778,0.0003695064,0.000141615,0.001034414,0.0001620467],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009075663,"about_ca_system_score_gemma":0.0005540795,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001371756,"about_ca_topic_score_gemma":0.0001658794,"domain_scores_codex":[0.9941695,0.0009480661,0.0007580668,0.0008157349,0.002088802,0.001219825],"domain_scores_gemma":[0.9972724,0.000448445,0.0001551616,0.000884746,0.000657721,0.0005815154],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006435044,0.003769243,0.07420228,0.00114712,0.01062669,0.0004733933,0.01335149,0.00000291684,0.5768489,0.0007188126,0.008862807,0.3035613],"study_design_scores_gemma":[0.005542626,0.001154803,0.1930594,0.000724532,0.000772392,0.00003878403,0.0006691036,0.0004218599,0.7959082,0.0006694846,0.0006580347,0.0003808724],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9776231,0.01631726,0.00001660281,0.001496513,0.0001121763,0.00370597,0.00009999275,0.00004730438,0.0005810898],"genre_scores_gemma":[0.9976564,0.000995765,0.00005409021,0.00004212414,0.0003983018,0.0005651311,0.0002122746,0.00006500594,0.00001089188],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3031805,"threshold_uncertainty_score":0.9999411,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1407907065609578,"score_gpt":0.3996701358644429,"score_spread":0.2588794293034851,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}