{"id":"W2765156675","doi":"","title":"Abstract 261: Liver-specific Pcsk9 Knockout And Transgenic Mice","year":2007,"lang":"en","type":"article","venue":"Circulation","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"Medicine; PCSK9; Genetically modified mouse; Knockout mouse; Transgene; LDL receptor; Internal medicine; Cholesterol; Receptor; Lipoprotein; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007534085,0.003071402,0.001171351,0.002989091,0.001220648,0.0009683785,0.001350587,0.002500649,0.02202927],"category_scores_gemma":[0.0003524959,0.001520817,0.001141141,0.001080492,0.0014602,0.0008317018,0.0009927379,0.00375353,0.01370897],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001086065,"about_ca_system_score_gemma":0.0005584533,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000797727,"about_ca_topic_score_gemma":0.001021615,"domain_scores_codex":[0.9991338,0.00007300551,0.0001196135,0.00029118,0.0002389767,0.0001435453],"domain_scores_gemma":[0.9988554,0.00009460633,0.0004890221,0.0001090397,0.00006897547,0.000383042],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002145596,0.0004612659,0.0002450026,0.0001908031,0.00003738925,0.0008459518,0.00009983055,0.0002330454,0.9889662,0.001623798,0.001606475,0.00354472],"study_design_scores_gemma":[0.002357838,0.002085895,0.008383543,0.0001910212,0.0003312723,0.005825546,0.0001388907,0.002786896,0.936125,0.001301207,0.0403387,0.0001340836],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8827884,0.003805159,0.02910811,0.003657264,0.00151596,0.001129437,0.04412576,0.005216076,0.02865405],"genre_scores_gemma":[0.6701832,0.006127114,0.03845718,0.001299529,0.0008909676,0.00209028,0.03839524,0.00337112,0.2391854],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02202927,"threshold_uncertainty_score":0.0736953,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02670351979005559,"score_gpt":0.2618306009993474,"score_spread":0.2351270812092918,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}