{"id":"W2765359194","doi":"10.1016/j.bbamem.2017.10.019","title":"Membrane biology visualized in nanometer-sized discs formed by styrene maleic acid polymers","year":2017,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Biomembranes","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"National Cancer Institute; Biotechnology and Biological Sciences Research Council; Alberta Innovates Bio Solutions","keywords":"Maleic acid; Membrane; Membrane protein; Transmembrane protein; Polymer; Nanodisc; Lipid bilayer; SMA*; Nanotechnology; Biophysics; Materials science; Structural biology; Peripheral membrane protein; Chemistry; Integral membrane protein; Biochemistry; Biology; Copolymer; Computer science; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0004839996,0.002196079,0.004258853,0.0008768708,0.0003637821,0.0003144064,0.002680693,0.002182307,0.000155523],"category_scores_gemma":[0.0001691193,0.00174769,0.00194488,0.0007932793,0.001042982,0.00005831731,0.0008794087,0.0007750105,0.00007376113],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001092766,"about_ca_system_score_gemma":0.0008384616,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001647598,"about_ca_topic_score_gemma":0.00007027519,"domain_scores_codex":[0.9925866,0.0007484547,0.001888886,0.002614812,0.0004838392,0.001677373],"domain_scores_gemma":[0.9948193,0.0001215626,0.001735007,0.00272733,0.0001093779,0.00048745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002646992,0.0004012268,0.00000110933,0.003896655,0.0006291402,0.00001505972,0.00004971713,2.23541e-8,0.9111384,0.00001912837,0.0004276141,0.08315722],"study_design_scores_gemma":[0.001935456,0.0004169618,0.00001416184,0.001152093,0.0008793063,0.00005395746,0.00001936656,7.072987e-7,0.5621988,0.000009078592,0.4316947,0.001625487],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.222472,0.7673011,0.000007648777,0.0003792906,0.001937842,0.002872453,0.004221611,0.0001599191,0.0006480719],"genre_scores_gemma":[0.07166735,0.9083624,0.0001282131,0.0002271476,0.0009736361,0.0005366412,0.01576641,0.0003623318,0.001975841],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.4312671,"threshold_uncertainty_score":0.9991131,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03937178229278736,"score_gpt":0.3699888297337999,"score_spread":0.3306170474410126,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}