{"id":"W2765467460","doi":"10.1002/anie.201709059","title":"Intramolecular Thioether Migration in the Rhodium‐Catalyzed Ene‐Cycloisomerization of Alkenylidenecyclopropanes by a Metal‐Mediated β‐Sulfide Elimination","year":2017,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Sulfur-Based Synthesis Techniques","field":"Chemistry","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada; AstraZeneca; Canada Research Chairs; Royal Society; Engineering and Physical Sciences Research Council; China Scholarship Council","keywords":"Cycloisomerization; Allylic rearrangement; Sulfide; Thioether; Intramolecular force; Chemistry; Rhodium; Ene reaction; Catalysis; Selenide; Sulfur; Medicinal chemistry; Stereochemistry; Photochemistry; Combinatorial chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001831394,0.0004231937,0.000123408,0.0001188459,0.000157969,0.0001608794,0.0002110064,0.0002002184,0.001495823],"category_scores_gemma":[0.0001199921,0.0001113751,0.0001764051,0.00009642903,0.0002211177,0.0002551565,0.0002399496,0.0004416906,0.0005113634],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000146846,"about_ca_system_score_gemma":0.0003025367,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003795529,"about_ca_topic_score_gemma":0.001025344,"domain_scores_codex":[0.9999079,0.00001195493,0.000006054376,0.00001892289,0.00001848183,0.00003667162],"domain_scores_gemma":[0.9999608,0.000007730343,0.00001008599,0.000007058259,0.000007271209,0.00000706645],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001224813,0.00008737753,0.0003941985,0.0001723937,0.00002529854,0.0006520125,0.0001744418,0.0003473731,0.9814748,0.002585936,0.0004539145,0.01350975],"study_design_scores_gemma":[0.00001347553,0.0003430145,0.0006642635,0.000007307211,0.00001571462,0.0004589636,0.00003276768,0.0006633076,0.992305,0.000117528,0.005369736,0.000008938173],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9672467,0.001318177,0.008652247,0.0002291642,0.00009088606,0.00006510007,0.000113301,0.0001217935,0.02216269],"genre_scores_gemma":[0.9948791,0.0005798984,0.001714109,0.00002507412,0.000008910686,0.00001152548,0.00006956909,0.00001165591,0.002700093],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001495823,"threshold_uncertainty_score":0.005004048,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01286425606055927,"score_gpt":0.2641122906803077,"score_spread":0.2512480346197484,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}